<entry xmlns="http://pdbe.org/empiar" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="https://ftp.ebi.ac.uk/pub/databases/emtest/empiar/schema/empiar.xsd" accessionCode="EMPIAR-13697" schemaVersion="0.65" public="true">
    <admin>
        <currentStatus>REL</currentStatus>
        <keyDates>
            <depositionDate>2026-06-17</depositionDate>
            <releaseDate>2026-06-29</releaseDate>
            <updateDate>2026-06-29</updateDate>
        </keyDates>
        <title>Single-Particle Cryo-EM of a Nucleosome Containing a Single-Strand Break at SHL −2.8 Bound to the Human PARP2 WGR Domain</title>
        <correspondingAuthor private="true">
            <authorORCID>0000-0002-0344-6265</authorORCID>
            <firstName>Tae Hun</firstName>
            <lastName>Kim</lastName>
            <organization type="academic">Case Western Reserve University</organization>
            <street>10900 Euclid Ave</street>
            <townOrCity>Cleveland</townOrCity>
            <stateOrProvince>Ohio</stateOrProvince>
            <country>United States</country>
            <postOrZipCode>44106</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator private="true">
            <authorORCID>0000-0002-0344-6265</authorORCID>
            <firstName>Tae Hun</firstName>
            <lastName>Kim</lastName>
            <organization type="academic">Department of Biochemistry, Case Western Reserve University</organization>
            <street>2109 Adelbert Road</street>
            <townOrCity>Cleveland</townOrCity>
            <stateOrProvince>Ohio</stateOrProvince>
            <country>United States</country>
            <postOrZipCode>44106</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author authorORCID="0000-0003-3658-6990">Jayathilake C</author>
            <author>Mewhinney CE</author>
            <author authorORCID="0000-0002-6874-2823">Gregory-Lott ER</author>
            <author authorORCID="0000-0001-5496-8381">Virk RK</author>
            <author>Nair R</author>
            <author>Yang J</author>
            <author authorORCID="0009-0004-7942-9156">Cho E</author>
            <author>Day AG</author>
            <author>Taylor DJ</author>
            <author authorORCID="0000-0002-0344-6265">Kim TH</author>
        </authorsList>
        <grantSupport>
            <grantReference>
                <fundingBody>National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)</fundingBody>
                <code>R35GM154859</code>
                <country>United States</country>
            </grantReference>
        </grantSupport>
        <datasetSize units="TB">2.2</datasetSize>
        <entryDOI>10.6019/EMPIAR-13697</entryDOI>
        <experimentType>EMDB</experimentType>
        <scale>molecule</scale>
    </admin>
    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-74561</emdbEntry>
            <emdbEntry>EMD-74562</emdbEntry>
            <emdbEntry>EMD-75074</emdbEntry>
            <emdbEntry>EMD-75075</emdbEntry>
            <emdbEntry>EMD-75079</emdbEntry>
            <emdbEntry>EMD-75080</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="false">
                    <author authorORCID="0000-0003-3658-6990" order="1">Jayathilake C</author>
                    <author order="2">Mewhinney CE</author>
                    <author authorORCID="0000-0002-6874-2823" order="3">Gregory-Lott ER</author>
                    <author authorORCID="0000-0001-5496-8381" order="4">Virk RK</author>
                    <author order="5">Nair R</author>
                    <author order="6">Yang J</author>
                    <author authorORCID="0009-0004-7942-9156" order="7">Cho E</author>
                    <author order="8">Day AG</author>
                    <author order="9">Taylor DJ</author>
                    <author authorORCID="0000-0002-0344-6265" order="10">Kim TH</author>
                    <title>High-Yield Production of Modified DNA Enables Structural Analysis of PARP2 Recognition of Nucleosomal Single-Strand Breaks</title>
                    <journal>Journal of molecular biology</journal>
                    <journalAbbreviation>J Mol Biol</journalAbbreviation>
                    <country></country>
                    <issue>10</issue>
                    <volume>438</volume>
                    <year>2026</year>
                    <language>English</language>
                    <externalReferences type="doi">10.1016/j.jmb.2026.169753</externalReferences>
                    <externalReferences type="pubmed">41819421</externalReferences>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>Unaligned multi-frame micrographs of a Nucleosome Containing a Single-Strand Break at SHL −2.8 Bound to the Human PARP2 WGR Domain</name>
        <directory>/data/movies_v2/Images-Disc1</directory>
        <category>micrographs - multiframe</category>
        <headerFormat>EER</headerFormat>
        <dataFormat>EER</dataFormat>
        <numImagesOrTiltSeries>3768</numImagesOrTiltSeries>
        <framesPerImage>40</framesPerImage>
        <voxelType>UNSIGNED 16 BIT INTEGER</voxelType>
        <dimensions>
            <imageWidth>4096</imageWidth>
            <pixelWidth>0.9105</pixelWidth>
            <imageHeight>4096</imageHeight>
            <pixelHeight>0.9105</pixelHeight>
        </dimensions>
        <details></details>
        <segmentationList/>
        <micrographsFilePattern></micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
</entry>
