REL 2026-04-14 2026-04-22 2026-04-22 0000-0002-2661-8226 Peng Ge Department of Biological Chemistry, UCLA Los Angeles California United States 90095 0000-0003-2432-5419 David S Eisenberg Department of Chemistry and Biochemistry, and Department of Biological Chemistry, UCLA; HHMI Los Angeles California United States 90095 Hou K Ge P Sawaya MR Lutter L Dolinsky JL Yang Y Jiang YX Boyer DR Cheng X Pi J Zhang J Lu J Abskharon R Yang S Yu Z Feigon J Eisenberg DS National Institutes of Health (NIH) 1R01AG070895 United States National Institutes of Health (NIH) RF1AG065407 United States 1.3 10.6019/EMPIAR-13489 EMDB molecule EMD-44185 Hou K Ge P Sawaya MR Lutter L Dolinsky JL Yang Y Jiang YX Boyer DR Cheng X Pi J Zhang J Lu J Abskharon R Yang S Yu Z Feigon J Eisenberg DS Nature Nature 8078 644 1020 1027 2025 English 10.1038/s41586-025-09244-z 40634605

Raw EER movies. Total dosage is 50 e/A2. Gain reference provided.

Tau Paired Helical Filament from Alzheimer's Disease incubated with D-peptide D-TLKIVWS /data/session1 micrographs - multiframe EER EER 296 2475 UNSIGNED BYTE 4096 0.94 4096 0.94

EER format movies with 2475 raw frames per movie. 50 e-/A2 dosage.

data/session1/4180-3*.eer Tau Paired Helical Filament from Alzheimer's Disease incubated with D-peptide D-TLKIVWS /data/session2 micrographs - multiframe EER EER 570 2898 UNSIGNED BYTE 4096 0.94 4096 0.94

EER format movies with 2898 raw frames per movie. 50 e-/A2 dosage.

data/session2/1075-3*.eer Tau Paired Helical Filament from Alzheimer's Disease incubated with D-peptide D-TLKIVWS /data/session3 micrographs - multiframe EER EER 619 1782 UNSIGNED BYTE 4096 0.94 4096 0.94

EER format movies with 1782 raw frames per movie. 50 e-/A2 dosage.

data/session3/1075-2*.eer