REL 2025-04-25 2026-03-05 2026-03-05 Structure of the human RalGAP2 complex 0000-0002-4922-4545 Christos Gatsogiannis Center for Soft Nanoscience and Institute of Medical Physics and Biophysics Busso-Peus-Str. 10 Münster NRW Germany 48149 0000-0002-4922-4545 Christos Gatsogiannis Center for Soft Nanoscience and Institute of Medical Physics and Biophysics Busso-Peus-Str. 10 Münster NRW Germany 48149 0000-0003-3950-5914 Daniel Kuemmel University of Muenster, Institute of Biochemistry Corrensstrasse 36 Muenster NRW Germany 48149 Rasche R Klink BU Chen M Gatsogiannis C Kümmel D German Research Foundation (DFG) KU2531/2 Germany German Research Foundation (DFG) KU2531/6 Germany German Research Foundation (DFG) 496113311 Germany German Research Foundation (DFG) CRC 1348 A15 Germany German Research Foundation (DFG) CRC1430 A04 Germany German Research Foundation (DFG) INST 211/667-1 Germany 52.0 10.6019/EMPIAR-13201 EMDB molecule EMD-53418 EMD-53419 EMD-53420 EMD-53421 EMD-53422 Rasche R Klink BU Apken LH Michalke E Chen M Oeckinghaus A Gatsogiannis C Kümmel D Structure and mechanism of the RalGAP tumor suppressor complex Nature communications Nat Commun Germany 2025 English 10.1038/s41467-025-61743-9
The EER movies are the unmodified raw movies with a total electron dose of 50 electrons per squared Angstrom.
 Unaligned Falcon 4i movies in Electron Event Representation (EER) /data/RalGap_EERs_4_EMPIAR/EER-Rawdata micrographs - multiframe EER EER 64592 0 1 999 BIT 16384 0.145 16384 0.145
Movies in Falcon 4i Electron Event Representation (EER). Particles in .mrcs format from the final, polished particle stack with 420.975 particles from a final RELION Particle (Re-)extraction job.
data/RalGap_EERs_4_EMPIAR/EER-Rawdata/2023*/Images-Disc1/GridSquare*/Data/*EER.eer data/RalGap_EERs_4_EMPIAR/Final_Particles/job209 data/RalGap_EERs_4_EMPIAR/Final_Particles/job209 Motion corrected micrographs of RalGap /data/RalGap_EERs_4_EMPIAR/MotionCorr-Data micrographs - single frame MRC MRC 64591 1 1 999 16 BIT FLOAT 4096 0.58 4096 0.58
Motion corrected micrographs of RalGap. The micrographs are the motion corrected average of 61-63 movie fractions, which were themself created from 793-819 EER movie frames. The accumulated electron dose was ~60 electrons per square Angstroem. Particles in .mrcs format from the final, polished particle stack with 420.975 particles from a final RELION Particle (Re-)extraction job.
data/RalGap_EERs_4_EMPIAR/MotionCorr-Data/MotCor_*/EER-links_* data/RalGap_EERs_4_EMPIAR/Final_Particles/job209 data/RalGap_EERs_4_EMPIAR/Final_Particles/job209