<entry xmlns="http://pdbe.org/empiar" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="https://ftp.ebi.ac.uk/pub/databases/emtest/empiar/schema/empiar.xsd" accessionCode="EMPIAR-13145" schemaVersion="0.65" public="true">
    <admin>
        <currentStatus>REL</currentStatus>
        <keyDates>
            <depositionDate>2025-11-21</depositionDate>
            <releaseDate>2025-12-16</releaseDate>
            <updateDate>2025-12-16</updateDate>
        </keyDates>
        <title>Cryo-electron tomography of mitochondria from untreated and G-TPP treated HeLa cells</title>
        <correspondingAuthor private="true">
            <authorORCID>0000-0002-8366-7622</authorORCID>
            <firstName>Rubén</firstName>
            <lastName>Fernández-Busnadiego</lastName>
            <organization type="academic">University Medical Center Göttingen, Institute for Neuropathology, Göttingen, Germany</organization>
            <townOrCity>Göttingen</townOrCity>
            <country>Germany</country>
            <postOrZipCode>37077</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator private="true">
            <authorORCID>0000-0002-8366-7622</authorORCID>
            <firstName>Rubén</firstName>
            <lastName>Fernández-Busnadiego</lastName>
            <organization type="academic">University Medical Center Göttingen, Institute for Neuropathology, Göttingen, Germany</organization>
            <townOrCity>Göttingen</townOrCity>
            <country>Germany</country>
            <postOrZipCode>37077</postOrZipCode>
        </principalInvestigator>
        <principalInvestigator private="true">
            <authorORCID>0000-0001-9733-2404</authorORCID>
            <firstName>Miratul</firstName>
            <lastName>Muqit</lastName>
            <organization type="academic">MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, UK</organization>
            <townOrCity>Dundee</townOrCity>
            <country>United Kingdom</country>
            <postOrZipCode>DD1 5EH</postOrZipCode>
        </principalInvestigator>
        <principalInvestigator private="true">
            <authorORCID>0000-0003-4082-4349</authorORCID>
            <firstName>Iban</firstName>
            <lastName>Ubarretxena-Belandia</lastName>
            <organization type="academic">Biofisika Institute (CSIC-UPV/EHU), University of the Basque Country, Leioa, Spain</organization>
            <townOrCity>Leioa</townOrCity>
            <country>Spain</country>
            <postOrZipCode>48940</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author authorORCID="0000-0002-8595-5994">Ehses K</author>
            <author>Lopez-Alonso JP</author>
            <author authorORCID="0000-0002-7325-3303">Antico O</author>
            <author authorORCID="0000-0002-2288-2986">Abdussalam A</author>
            <author authorORCID="0000-0001-9733-2404">Muqit MMK</author>
            <author authorORCID="0000-0003-4082-4349">Ubarretxena-Belandia I</author>
            <author authorORCID="0000-0002-8366-7622">Fernandez-Busnadiego R</author>
        </authorsList>
        <grantSupport>
            <grantReference>
                <fundingBody>German Research Foundation (DFG)</fundingBody>
                <code>448415290</code>
                <country>Germany</country>
            </grantReference>
            <grantReference>
                <fundingBody>Michael J. Fox Foundation</fundingBody>
                <code>MJFF-010458</code>
                <country>United States</country>
            </grantReference>
            <grantReference>
                <fundingBody>German Research Foundation (DFG)</fundingBody>
                <code>EXC 2067</code>
                <country>Germany</country>
            </grantReference>
            <grantReference>
                <fundingBody>Aligning Science Across Parkinson's (ASAP)</fundingBody>
                <code>ASAP-000282</code>
                <country>United States</country>
            </grantReference>
        </grantSupport>
        <datasetSize units="GB">1005.9</datasetSize>
        <entryDOI>10.6019/EMPIAR-13145</entryDOI>
        <experimentType>EMDB</experimentType>
        <scale>cell</scale>
    </admin>
    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-55203</emdbEntry>
            <emdbEntry>EMD-55204</emdbEntry>
            <emdbEntry>EMD-55205</emdbEntry>
            <emdbEntry>EMD-55206</emdbEntry>
            <emdbEntry>EMD-55207</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="true">
                    <author authorORCID="0000-0002-8595-5994" order="1">Ehses K</author>
                    <author order="2">López-Alonso JP</author>
                    <author authorORCID="0000-0002-7325-3303" order="3">Antico O</author>
                    <author authorORCID="0000-0002-2288-2986" order="4">Azem A</author>
                    <author authorORCID="0000-0001-9733-2404" order="5">Muqit MM</author>
                    <author authorORCID="0000-0003-4082-4349" order="6">Ubarretxena-Belandia I</author>
                    <author authorORCID="0000-0002-8366-7622" order="7">Fernández-Busnadiego R</author>
                    <title>Structural remodeling of the mitochondrial protein biogenesis machinery under proteostatic stress</title>
                    <journal>bioRxiv</journal>
                    <journalAbbreviation></journalAbbreviation>
                    <country></country>
                    <year>2025</year>
                    <externalReferences type="doi">10.1101/2025.10.06.680693</externalReferences>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>Motion-corrected frames from acquired tilt-series</name>
        <directory>/data/frames</directory>
        <category>tilt series</category>
        <headerFormat>MRC</headerFormat>
        <dataFormat>MRC</dataFormat>
        <numImagesOrTiltSeries>242</numImagesOrTiltSeries>
        <framesPerImage>1</framesPerImage>
        <voxelType>32 BIT FLOAT</voxelType>
        <dimensions>
            <imageWidth>4096</imageWidth>
            <pixelWidth>2.3124</pixelWidth>
            <imageHeight>4096</imageHeight>
            <pixelHeight>2.3124</pixelHeight>
        </dimensions>
        <details>- frames: Contains the motion-corrected frames corresponding to the 242 tilt series used in this - mdocs: Contains the processed .mdoc files for the 242 tilt series. These files were reorganized and reformatted to be compatible with our processing workflow.
- raw_mdocs: Contains the original, unmodified .mdoc files exactly as obtained during data acquisition.</details>
        <segmentationList/>
        <micrographsFilePattern></micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
</entry>
