REL 2025-10-06 2025-10-15 2025-10-15 0000-0001-9251-1374 Paul Lapios Interdisciplinary Institute for Neurosciences 146 rue Leo Saignat Bordeaux Nouvelle-Aquitaine France 33000 0000-0002-5878-5408 David Perrais Interdisciplinary Institute for Neurosciences 146 rue Leo Saignat Bordeaux France 33000 0000-0002-0058-6959 Etienne Herzog Interdisciplinary Institute for Neurosciences 146 rue Leo Saignat Bordeaux France 33000 0000-0003-3031-9824 Remi Fronzes European Institute for Chemistry and Biology 2 Rue Robert Escarpit Pessac France 33600 Paul Lapios PL Robin Anger RA Vincent Paget-Blanc VPB Esther Marza EM Vladan Lucic VL Remi Fronzes RF Etienne Herzog EH David Perrais DP Agence Nationale de la Recherche (ANR) ANR-19-CE16-0003 France Agence Nationale de la Recherche (ANR) ANR-20-CE14-0020-03 France Agence Nationale de la Recherche (ANR) ANR-24-CE16-5973- 01 France 133.0 10.6019/EMPIAR-13028 ssET cell Paul Lapios PL Robin Anger RA Vincent Paget-Blanc VPB Esther Marza EM Vladan Lucic VL Remi Fronzes RF Etienne Herzog EH David Perrais DP Tomograms and 3D models of dopaminergic (DA), glutamatergic (GLU), hub synapses (DHS). /data reconstructed volumes MRC MRC 400 1 32 BIT FLOAT variable 15.59 variable 15.59

Reconstructed tomograms are accompanied by 3D models, manually segmented with 3dmod. The color code helps to identify the dopaminergic (magenta) or glutamatergic (green) synaptosome.