Cryo-EM SPA dataset of the human nucleosome with the H2AX variant

REL 2025-09-11 2025-10-30 2025-10-30 Cryo-EM SPA dataset of the human nucleosome with the H2AX variant 0000-0002-1727-9269 Rashmi Panigrahi Department of Biochemistry, University of Alberta Edmonton Alberta Canada T6G 2R3 0000-0002-1727-9269 Rashmi Panigrahi Department of Biochemistry, University of Alberta Edmonton Alberta Canada T6G 2R3 0000-0003-2733-7052 John Newman Mark Glover Department of Biochemistry, University of Alberta Edmonton Alberta Canada T6G 2R3 Panigrahi R Edwards RA Glover JNM Canadian Institutes of Health Research (CIHR) CIHR 426213 Canada National Institutes of Health (NIH) R01 CA121245-06A1 United States 5.7 10.6019/EMPIAR-12976 EMDB molecule EMD-48392 EMD-48403 EMD-48394 EMD-48395 EMD-48396 Panigrahi R Edwards R Islam MT Lu J Kulepa A Kim TH Mark Glover JN Structural insights into γH2Ax containing nucleosomes Nucleic acids research Nucleic Acids Res 19 53 2025 English 10.1093/nar/gkaf1028 41123210 Unaligned multi-frame micrographs of H2AX containing nucleosome /data/s1_20210909 micrographs - multiframe EER EER 4800 50 BIT 4096 0.77 4096 0.77

Raw movies total exposure does 50 e/A^2

Unaligned multi-frame micrographs of H2AX containing nucleosome /data/s1_20211216 micrographs - multiframe EER EER 618 50 BIT 4096 0.77 4096 0.77

Raw movies total exposure does 50 e/A^2 collected at a tilt angle of 17 degrees

Unaligned multi-frame micrographs of H2AX containing nucleosome /data/s1_20220105 micrographs - multiframe EER EER 3068 50 BIT 4096 0.77 4096 0.77

Raw movies total exposure does 50 e/A^2 collected at a tilt angle of 35 degrees

Unaligned multi-frame micrographs of H2AX containing nucleosome /data/s1_20220106 micrographs - multiframe EER EER 1349 50 BIT 4096 0.77 4096 0.77

Raw movies total exposure does 50 e/A^2 collected at a tilt angle of 35 degrees