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    <admin>
        <currentStatus>REL</currentStatus>
        <keyDates>
            <depositionDate>2025-08-18</depositionDate>
            <releaseDate>2026-04-28</releaseDate>
            <updateDate>2026-04-28</updateDate>
        </keyDates>
        <title>Human Argonaute1 WT with BS3</title>
        <correspondingAuthor private="true">
            <authorORCID>0000-0002-1581-9321</authorORCID>
            <firstName>Andrew</firstName>
            <lastName>Savidge</lastName>
            <organization type="academic">The Ohio State University, Department of Chemistry and Biochemistry</organization>
            <street>496 West 12th Avenue</street>
            <townOrCity>Columbus</townOrCity>
            <stateOrProvince>Ohio</stateOrProvince>
            <country>United States</country>
            <postOrZipCode>43210</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator private="true">
            <authorORCID>0000-0002-9857-6010</authorORCID>
            <firstName>Kotaro</firstName>
            <lastName>Nakanishi</lastName>
            <organization type="academic">The Ohio State University, Department of Chemistry and Biochemistry</organization>
            <street>496 West 12th Avenue</street>
            <townOrCity>Columbus</townOrCity>
            <stateOrProvince>Ohio</stateOrProvince>
            <country>United States</country>
            <postOrZipCode>43210</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author authorORCID="0000-0002-1581-9321">Savidge A</author>
            <author authorORCID="0000-0002-9857-6010">Nakanishi K</author>
            <author authorORCID="0000-0002-3707-2265">Shen Z</author>
            <author authorORCID="0000-0002-6281-1752">Fu T</author>
            <author authorORCID="0000-0002-6589-2770">Adhav V</author>
        </authorsList>
        <grantSupport>
            <grantReference>
                <fundingBody></fundingBody>
                <code></code>
                <country></country>
            </grantReference>
        </grantSupport>
        <datasetSize units="TB">1.2</datasetSize>
        <entryDOI>10.6019/EMPIAR-12940</entryDOI>
        <experimentType>EMDB</experimentType>
        <scale>molecule</scale>
    </admin>
    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-72193</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="false">
                    <author authorORCID="0000-0002-1581-9321" order="1">Savidge A</author>
                    <author authorORCID="0000-0001-9627-3422" order="2">Zhang H</author>
                    <author order="3">Annasaheb Adhav V</author>
                    <author authorORCID="0000-0003-2160-173X" order="4">Kehling AC</author>
                    <author authorORCID="0000-0002-4850-6348" order="5">Sim G</author>
                    <author authorORCID="0000-0002-3707-2265" order="6">Shen Z</author>
                    <author authorORCID="0000-0002-6281-1752" order="7">Fu TM</author>
                    <author authorORCID="0000-0002-9857-6010" order="8">Nakanishi K</author>
                    <title>Neurodevelopmental disorder-linked Argonaute mutations permit delayed RISC formation and unusual shortening of miRNAs by 3'→5' trimming</title>
                    <journal>Proceedings of the National Academy of Sciences of the United States of America</journal>
                    <journalAbbreviation>Proc Natl Acad Sci U S A</journalAbbreviation>
                    <country></country>
                    <issue>46</issue>
                    <volume>122</volume>
                    <year>2025</year>
                    <language>English</language>
                    <externalReferences type="doi">10.1073/pnas.2524644122</externalReferences>
                    <externalReferences type="pubmed">41237208</externalReferences>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>Unaligned unprocessed movies of AGO1 WT</name>
        <directory>/data/Images-Disc1</directory>
        <category>micrographs - multiframe</category>
        <headerFormat>TIFF</headerFormat>
        <dataFormat>TIFF</dataFormat>
        <numImagesOrTiltSeries>2453</numImagesOrTiltSeries>
        <framesPerImage>50</framesPerImage>
        <frameRange>
            <frameRangeMin>1</frameRangeMin>
            <frameRangeMax>50</frameRangeMax>
        </frameRange>
        <voxelType>SIGNED 16 BIT INTEGER</voxelType>
        <dimensions>
            <imageWidth>8184</imageWidth>
            <pixelWidth>0.448</pixelWidth>
            <imageHeight>11520</imageHeight>
            <pixelHeight>0.448</pixelHeight>
        </dimensions>
        <details>Data analysis used the TIFF stacks under the name "*fractions.tiff".</details>
        <segmentationList/>
        <micrographsFilePattern>data</micrographsFilePattern>
        <pickedParticlesFilePattern>data/Images-Disc1/GridSquare_*/Data/*fractions.tiff</pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
</entry>
