<entry xmlns="http://pdbe.org/empiar" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="https://ftp.ebi.ac.uk/pub/databases/emtest/empiar/schema/empiar.xsd" accessionCode="EMPIAR-12800" schemaVersion="0.65" public="true">
    <admin>
        <currentStatus>REL</currentStatus>
        <keyDates>
            <depositionDate>2025-05-28</depositionDate>
            <releaseDate>2025-09-04</releaseDate>
            <updateDate>2025-09-04</updateDate>
        </keyDates>
        <title>Particle stacks from ANP amyloids from left atrial appendage of atrial fibrillation patient</title>
        <correspondingAuthor private="true">
            <authorORCID>0000-0003-3287-9024</authorORCID>
            <firstName>Antonio</firstName>
            <lastName>Chaves-Sanjuan</lastName>
            <organization type="academic">Department of Biosciences, University of Milan</organization>
            <townOrCity>Milan</townOrCity>
            <country>Italy</country>
            <postOrZipCode>20133</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator private="true">
            <authorORCID>0000-0001-6678-5873</authorORCID>
            <firstName>Stefano</firstName>
            <lastName>Ricagno</lastName>
            <organization type="academic">Department of Biosciences, University of Milan</organization>
            <townOrCity>Milan</townOrCity>
            <country>Italy</country>
            <postOrZipCode>20133</postOrZipCode>
        </principalInvestigator>
        <principalInvestigator private="true">
            <authorORCID>0000-0003-3287-9024</authorORCID>
            <firstName>Antonio</firstName>
            <lastName>Chaves-Sanjuan</lastName>
            <organization type="academic">Department of Biosciences, University of Milan</organization>
            <townOrCity>Milan</townOrCity>
            <country>Italy</country>
            <postOrZipCode>20133</postOrZipCode>
        </principalInvestigator>
        <principalInvestigator private="true">
            <authorORCID>0000-0001-9472-6854</authorORCID>
            <firstName>Luca</firstName>
            <lastName>Broggini</lastName>
            <organization type="academic">Department of Biosciences, University of Milan</organization>
            <townOrCity>Milan</townOrCity>
            <country>Italy</country>
            <postOrZipCode>20133</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author authorORCID="0000-0001-9472-6854">Broggini L</author>
            <author authorORCID="0000-0003-3287-9024">Chaves-Sanjuan A</author>
            <author authorORCID="0000-0001-6678-5873">Ricagno S</author>
        </authorsList>
        <grantSupport>
            <grantReference>
                <fundingBody>Fondazione CARIPLO</fundingBody>
                <code>GJC23044</code>
                <country>Italy</country>
            </grantReference>
            <grantReference>
                <fundingBody>Ministero dell Universita e della Ricerca</fundingBody>
                <code>20207XLJB2</code>
                <country>Italy</country>
            </grantReference>
        </grantSupport>
        <datasetSize units="GB">492.9</datasetSize>
        <entryDOI>10.6019/EMPIAR-12800</entryDOI>
        <experimentType>EMDB</experimentType>
        <scale>molecule</scale>
    </admin>
    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-53891</emdbEntry>
            <emdbEntry>EMD-53910</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="false" preprint="false">
                    <author authorORCID="0000-0001-9472-6854" order="1">Broggini L</author>
                    <author authorORCID="0000-0003-3287-9024" order="2">Chaves-Sanjuan A</author>
                    <author authorORCID="0000-0001-6678-5873" order="3">Ricagno S</author>
                    <title>Cryo-EM structure of ANP amyloids from left atrial appendage of atrial fibrillation patient</title>
                    <journal></journal>
                    <journalAbbreviation></journalAbbreviation>
                    <country></country>
                    <details>Particle stacks of the initial and the final set of segments used in the deposited reconstructions.</details>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>Initial particle stack extracted form start to end picking</name>
        <directory>/data/initial_particles</directory>
        <category>picked particles - multiframe - unprocessed</category>
        <headerFormat>MRCS</headerFormat>
        <dataFormat>MRCS</dataFormat>
        <numImagesOrTiltSeries>726989</numImagesOrTiltSeries>
        <framesPerImage>40</framesPerImage>
        <voxelType>32 BIT FLOAT</voxelType>
        <dimensions>
            <imageWidth>400</imageWidth>
            <pixelWidth>0.839</pixelWidth>
            <imageHeight>400</imageHeight>
            <pixelHeight>0.839</pixelHeight>
        </dimensions>
        <details>Particle stack coming from an extraction job of relion and the initial start-to-end fibrils picks. The particles are unbined. Inside the folder there is a particle.star and a "movies" folder containing the associated *.mrcs files</details>
        <segmentationList/>
        <micrographsFilePattern></micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
    <imageSet>
        <name>Particle stack of the final reconstructed ANP amyloids from left atrial appendage of atrial fibrillation patient - polymorph A</name>
        <directory>/data/EMD-53891_PolA_particles</directory>
        <category>picked particles - multiframe - processed</category>
        <headerFormat>MRCS</headerFormat>
        <dataFormat>MRCS</dataFormat>
        <numImagesOrTiltSeries>67547</numImagesOrTiltSeries>
        <framesPerImage>40</framesPerImage>
        <voxelType>UNSIGNED BYTE</voxelType>
        <dimensions>
            <imageWidth>400</imageWidth>
            <pixelWidth>0.839</pixelWidth>
            <imageHeight>400</imageHeight>
            <pixelHeight>0.839</pixelHeight>
        </dimensions>
        <details>Particle stack with the final alignment of the final reconstructed ANP amyloids from left atrial appendage of atrial fibrillation patient - polymorph A corresponding to EMD-53891</details>
        <segmentationList/>
        <micrographsFilePattern></micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
    <imageSet>
        <name>Particle stack of the final reconstructed ANP amyloids from left atrial appendage of atrial fibrillation patient - polymorph B</name>
        <directory>/data/EMD-53910_PolB_particles</directory>
        <category>picked particles - multiframe - processed</category>
        <headerFormat>MRCS</headerFormat>
        <dataFormat>MRCS</dataFormat>
        <numImagesOrTiltSeries>31454</numImagesOrTiltSeries>
        <framesPerImage>40</framesPerImage>
        <voxelType>32 BIT FLOAT</voxelType>
        <dimensions>
            <imageWidth>400</imageWidth>
            <pixelWidth>0.839</pixelWidth>
            <imageHeight>400</imageHeight>
            <pixelHeight>0.839</pixelHeight>
        </dimensions>
        <details>Particle stack with the final alignment of the final reconstructed ANP amyloids from left atrial appendage of atrial fibrillation patient - polymorph A corresponding to EMD-53910</details>
        <segmentationList/>
        <micrographsFilePattern></micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
</entry>
