<entry xmlns="http://pdbe.org/empiar" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="https://ftp.ebi.ac.uk/pub/databases/emtest/empiar/schema/empiar.xsd" accessionCode="EMPIAR-12632" schemaVersion="0.65" public="true">
    <admin>
        <currentStatus>REL</currentStatus>
        <keyDates>
            <depositionDate>2025-03-01</depositionDate>
            <releaseDate>2025-07-25</releaseDate>
            <updateDate>2025-07-25</updateDate>
        </keyDates>
        <title>Raw .tiff images of Panx1 containing c-terminal activating domain stack 2</title>
        <correspondingAuthor private="true">
            <authorORCID>0000-0002-5005-2031</authorORCID>
            <firstName>Toshi</firstName>
            <lastName>Kawate</lastName>
            <organization type="academic">Cornell University</organization>
            <street>930 Campus Rd</street>
            <townOrCity>Ithaca</townOrCity>
            <stateOrProvince>NY</stateOrProvince>
            <country>United States</country>
            <postOrZipCode>14853</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator private="true">
            <authorORCID>0000-0002-5005-2031</authorORCID>
            <firstName>Toshi</firstName>
            <lastName>Kawate</lastName>
            <organization type="academic">Cornell University</organization>
            <street>930 Campus Rd</street>
            <townOrCity>Ithaca</townOrCity>
            <stateOrProvince>NY</stateOrProvince>
            <country>United States</country>
            <postOrZipCode>14853</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author authorORCID="0000-0002-8761-7198">Ehrlich JJ</author>
            <author authorORCID="0000-0002-5005-2031">Kawate T</author>
        </authorsList>
        <grantSupport>
            <grantReference>
                <fundingBody>National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)</fundingBody>
                <code>R01GM114379</code>
                <country>United States</country>
            </grantReference>
        </grantSupport>
        <datasetSize units="TB">1.8</datasetSize>
        <entryDOI>10.6019/EMPIAR-12632</entryDOI>
        <experimentType>EMDB</experimentType>
        <scale>molecule</scale>
    </admin>
    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-45056</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="false">
                    <author authorORCID="0000-0002-8761-7198" order="1">Ehrlich JJ</author>
                    <author authorORCID="0000-0002-5005-2031" order="2">Kawate T</author>
                    <title>The C-terminal activating domain promotes pannexin 1 channel opening</title>
                    <journal>Proceedings of the National Academy of Sciences of the United States of America</journal>
                    <journalAbbreviation>Proc Natl Acad Sci U S A</journalAbbreviation>
                    <country></country>
                    <issue>51</issue>
                    <volume>121</volume>
                    <year>2024</year>
                    <language>English</language>
                    <externalReferences type="doi">10.1073/pnas.2411898121</externalReferences>
                    <externalReferences type="pubmed">39671183</externalReferences>
                    <details>This is the second stack of raw .tiff micrographs making up EMD-45056. Images were collect on at 300 kV on a Titan Krios with K3 direct electron detector. Raw pixel size is 0.535, spherical aberration 2.7. Flip gain upside down.</details>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>Raw micrographs of Pannexin 1 containing c-terminal activating domain, stack 2/2</name>
        <directory>/data</directory>
        <category>micrographs - multiframe</category>
        <headerFormat>TIFF</headerFormat>
        <dataFormat>TIFF</dataFormat>
        <numImagesOrTiltSeries>3340</numImagesOrTiltSeries>
        <framesPerImage>50</framesPerImage>
        <voxelType>UNSIGNED BYTE</voxelType>
        <dimensions>
            <imageWidth>11520</imageWidth>
            <pixelWidth>0.535</pixelWidth>
            <imageHeight>8184</imageHeight>
            <pixelHeight>0.535</pixelHeight>
        </dimensions>
        <details>Second of two (randomly organized) stacks of images used to generate EMD-45056. Raw unprocessed micrographs containing 50 frames over 50 e-/pix/sec. Gain is included in .mrc format and should be flipped upside down. Images were collected on a 300 kV Titan Krios with a K3 direct electron detector and BioQuantuum energy filter with a slit set to 15 eV. No objective aperture was used. Spherical aberration is 2.7.</details>
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        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
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