REL
2025-02-25
2025-04-24
2025-04-24
Cryo-EM of SARS-CoV-2 nsp13-replication-transcription complex (nsp13-RTC) (no detergent)
0000-0002-8241-3153
Seth
A
Darst
The Rockefeller University
1230 York Avenue
New York
NY
United States
10065
0000-0002-8241-3153
Seth
A
Darst
The Rockefeller University
1230 York Avenue
New York
NY
United States
10065
Chen J
Malone B
Llwewllyn E
Grasso M
Shelton PMM
Olinares PDB
Maruthi K
ENG ET
Vatandaslar H
Chait BT
Kapoor TM
Darst SA
Campbell EA
National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)
P41 GM103310
United States
National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)
U24 GM129539
United States
Simons Foundation
SF349247
United States
National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)
P41 GM109824
United States
National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)
P41 GM103314
United States
National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)
R35 GM130234
United States
National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)
R35 GM118130
United States
National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)
R01 GM114450
United States
3.2
10.6019/EMPIAR-12629
EMDB
molecule
EMD-49420
Chen J
Malone B
Llwewllyn E
Grasso M
Shelton PMM
Olinares PDB
Maruthi K
ENG ET
Vatandaslar H
Chait BT
Kapoor TM
Darst SA
Campbell EA
Structural basis for helicase-polymerase coupling in the SARS-CoV-2 replication-transcription complex
Cell
Cell
United States
6
182
1560
1573
2020
English
10.1016/j.cell.2020.07.033
32783916
unaligned raw movies
/data/rawdata
micrographs - multiframe
TIFF
TIFF
4358
50
UNSIGNED BYTE
5760
1.1
4092
1.1
FEI Titan Krios + Gatan K3, counting mode, BioQuantum energy filter 20 eV slit, Cs 2.7 mm; accelerating voltage 300 kV; dose rate 24.7 e-/ A^2/s, frame time 0.05 s (50 frames) with total exposure of 2.5 s, total dose of 64 e-/A^2; pixel size 1.1 A/px(detector); defocus range -0.8 to -2.5 um; for gain reference, see data/rawdata/references/reference_list.txt.
data/rawdata/20may26a_00019sq_v02_00002hln_00002enn.frames.tif