<entry xmlns="http://pdbe.org/empiar" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="https://ftp.ebi.ac.uk/pub/databases/emtest/empiar/schema/empiar.xsd" accessionCode="EMPIAR-12563" schemaVersion="0.65" public="true">
    <admin>
        <currentStatus>REL</currentStatus>
        <keyDates>
            <depositionDate>2025-02-18</depositionDate>
            <releaseDate>2025-03-05</releaseDate>
            <updateDate>2025-03-05</updateDate>
        </keyDates>
        <title>Cryo-EM micrographs of purified human BIRC6 in presence of HTRA2</title>
        <correspondingAuthor private="true">
            <authorORCID>0000-0003-0293-1063</authorORCID>
            <firstName>Juraj</firstName>
            <lastName>Ahel</lastName>
            <organization type="academic">IMP Vienna</organization>
            <townOrCity>Vienna</townOrCity>
            <country>Austria</country>
            <postOrZipCode>1030</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator private="true">
            <authorORCID>0000-0003-1582-6924</authorORCID>
            <firstName>Tim</firstName>
            <lastName>Clausen</lastName>
            <organization type="academic">IMP Vienna</organization>
            <townOrCity>Vienna</townOrCity>
            <country>Austria</country>
            <postOrZipCode>1030</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author authorORCID="0000-0003-2518-5681">Ehrmann JF</author>
            <author authorORCID="0000-0003-0216-7085">Grabarczyk DB</author>
            <author authorORCID="0000-0003-1582-6924">Clausen T</author>
        </authorsList>
        <grantSupport>
            <grantReference>
                <fundingBody></fundingBody>
                <code></code>
                <country></country>
            </grantReference>
        </grantSupport>
        <datasetSize units="GB">552.7</datasetSize>
        <entryDOI>10.6019/EMPIAR-12563</entryDOI>
        <experimentType>EMDB</experimentType>
        <scale>molecule</scale>
    </admin>
    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-15672</emdbEntry>
            <emdbEntry>EMD-15663</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="false">
                    <author authorORCID="0000-0003-2518-5681" order="1">Ehrmann JF</author>
                    <author authorORCID="0000-0003-0216-7085" order="2">Grabarczyk DB</author>
                    <author order="3">Heinke M</author>
                    <author order="4">Deszcz L</author>
                    <author order="5">Kurzbauer R</author>
                    <author authorORCID="0000-0003-1099-0741" order="6">Hudecz O</author>
                    <author order="7">Shulkina A</author>
                    <author order="8">Gogova R</author>
                    <author order="9">Meinhart A</author>
                    <author authorORCID="0000-0002-6150-2165" order="10">Versteeg GA</author>
                    <author authorORCID="0000-0003-1582-6924" order="11">Clausen T</author>
                    <title>Structural basis for regulation of apoptosis and autophagy by the BIRC6/SMAC complex</title>
                    <journal>Science (New York, N.Y.)</journal>
                    <journalAbbreviation>Science</journalAbbreviation>
                    <country></country>
                    <issue>6637</issue>
                    <volume>379</volume>
                    <firstPage>1117</firstPage>
                    <lastPage>1123</lastPage>
                    <year>2023</year>
                    <language>English</language>
                    <externalReferences type="doi">10.1126/science.ade8873</externalReferences>
                    <externalReferences type="pubmed">36758105</externalReferences>
                    <details>1) reconstructed micrographs, from motion correction and dose-weighted averaging of movies collected by a Titan Krios equipped with a Falcon4 camera

2) relion .star file(s) describing the particles used in the final reconstruction of the associated EMDB entries</details>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>Aligned motion-corrected dose-weighted micrograph averages of BIRC6 with HTRA1</name>
        <directory>/data</directory>
        <category>micrographs - single frame</category>
        <headerFormat>MRC</headerFormat>
        <dataFormat>MRC</dataFormat>
        <numImagesOrTiltSeries>8842</numImagesOrTiltSeries>
        <framesPerImage>1</framesPerImage>
        <voxelType>32 BIT FLOAT</voxelType>
        <dimensions>
            <imageWidth>4096</imageWidth>
            <pixelWidth>1.17</pixelWidth>
            <imageHeight>4096</imageHeight>
            <pixelHeight>1.17</pixelHeight>
        </dimensions>
        <details># /motioncorr/
Contains all motioncorrected dose-weighted micrograph averages for this data collection

# /EMD-15663/run_data.star
Relion star file describing all the particles from this dataset that were used in reconstruction of EMD-15663.
(Note: the EMD-15663 model is derived from 3 separate EMPIAR datasets. Each dataset includes a star file with the particles from that dataset only)

# /EMD-15663/run_data.star
Relion star file describing all the particles from this dataset that were used in reconstruction of EMD-15672.</details>
        <segmentationList/>
        <micrographsFilePattern>data/motioncorr/*mrc</micrographsFilePattern>
        <pickedParticlesFilePattern>data/EMD-*/run_data.star</pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
</entry>
