REL
2023-11-07
2026-07-07
2026-07-07
Integrin alpha-5 beta-1 in complex with BIIG2 Fab
0000-0003-1909-5751
Melody
Grace
Campbell
Fred Hutchinson Cancer Center
1100 Fairview Ave. N.
Seattle
WA
United States
98109
0000-0003-1909-5751
Melody
Grace
Campbell
Fred Hutchinson Cancer Center
1100 Fairview Ave N.
Seattle
WA
United States
98109
Nguyen AN
Campbell MGC
National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)
R35 GM147414-01
United States
3.7
10.6019/EMPIAR-12552
EMDB
molecule
EMD-44386
Nguyen AN
Heim JBH
Cordara GC
Chan MCC
Johannesen HJ
Charlesworth CC
Li ML
Azumaya CMA
Madden BM
Krengel UK
Campbell MGC
Meves AM
Structural and functional characterization of integrin α5-targeting antibodies for anti-angiogenic therapy
bioRxiv
United States
10.1101/2025.01.08.631572
Unaligned Frames of integrin a5b1 in complex with BIIG2 antibody fab fragment
/data/movies
micrographs - multiframe
TIFF
TIFF
3565
99
1
99
UNSIGNED BYTE
11520
0.561
8184
0.561
Tiff files containing the raw 99 movie frame (accumulating approximately 50 electron squared angstrom in a 6 second exposure.
data/movies/22mar09a_*en.frames.tif
data/particle_stack
Motion corrected frames of integrin a5b1 in complex with BIIG2 antibody fab fragment
/data/motion_corrected_micrographs
micrographs - single frame
MRC
MRC
3565
1
32 BIT FLOAT
5760
1.122
4092
1.122
Motion Corrected micrographs using MotionCorr2.
data/motion_corrected_micrographs/*.mrc
Movie Gain Refs
/data/Movie_gain_ref
micrographs - single frame
MRC
MRC
1
1
32 BIT FLOAT
11520
0.556
8184
0.556
Gain reference for movie collection in DM4 and MRC format
Polished particle of integrin a5b1 in complex with BIIG2 antibody fab fragment
/data/particle_stack
picked particles - single frame - processed
MRCS
MRCS
374814
1
UNSIGNED BYTE
352
1.122
352
1.122
Polished particles from RELION using particle polishing
data/motion_corrected_micrographs/*.mrc