<entry xmlns="http://pdbe.org/empiar" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="https://ftp.ebi.ac.uk/pub/databases/emtest/empiar/schema/empiar.xsd" accessionCode="EMPIAR-12524" schemaVersion="0.65" public="true">
    <admin>
        <currentStatus>REL</currentStatus>
        <keyDates>
            <depositionDate>2025-01-11</depositionDate>
            <releaseDate>2025-06-27</releaseDate>
            <updateDate>2025-06-27</updateDate>
        </keyDates>
        <title>Structure of the 55LCC ATPase complex</title>
        <correspondingAuthor private="true">
            <authorORCID>0000-0003-0239-5926</authorORCID>
            <firstName>Elton</firstName>
            <lastName>Zeqiraj</lastName>
            <organization type="academic">Astbury Centre for Structural Molecular Biology, University of Leeds</organization>
            <street>Woodhouse</street>
            <townOrCity>Leeds</townOrCity>
            <stateOrProvince>West Yorkshire</stateOrProvince>
            <country>United Kingdom</country>
            <postOrZipCode>LS2 9JT</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator private="true">
            <authorORCID>0000-0003-0239-5926</authorORCID>
            <firstName>Elton</firstName>
            <lastName>Zeqiraj</lastName>
            <organization type="academic">Astbury Centre for Structural Molecular Biology, University of Leeds</organization>
            <street>Woodhouse</street>
            <townOrCity>Leeds</townOrCity>
            <stateOrProvince>West Yorkshire</stateOrProvince>
            <country>United Kingdom</country>
            <postOrZipCode>LS2 9JT</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author authorORCID="0000-0001-9132-4737">Foglizzo M</author>
            <author authorORCID="0000-0002-1492-9481">Degtjarik O</author>
            <author authorORCID="0000-0003-0239-5926">Zeqiraj E</author>
        </authorsList>
        <grantSupport>
            <grantReference>
                <fundingBody>Medical Research Council (MRC, United Kingdom)</fundingBody>
                <code>MR/T029471/1</code>
                <country>United Kingdom</country>
            </grantReference>
            <grantReference>
                <fundingBody>Wellcome Trust</fundingBody>
                <code>222531/Z/21/Z</code>
                <country>United Kingdom</country>
            </grantReference>
            <grantReference>
                <fundingBody>Wellcome Trust</fundingBody>
                <code>221524/Z/20/Z</code>
                <country>United Kingdom</country>
            </grantReference>
        </grantSupport>
        <datasetSize units="TB">9.7</datasetSize>
        <entryDOI>10.6019/EMPIAR-12524</entryDOI>
        <experimentType>EMDB</experimentType>
        <scale>molecule</scale>
    </admin>
    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-19177</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="false">
                    <author authorORCID="0000-0001-8245-6877" order="1">Krishnamoorthy V</author>
                    <author authorORCID="0000-0001-9132-4737" order="2">Foglizzo M</author>
                    <author authorORCID="0000-0001-7358-9088" order="3">Dilley RL</author>
                    <author order="4">Wu A</author>
                    <author order="5">Datta A</author>
                    <author order="6">Dutta P</author>
                    <author order="7">Campbell LJ</author>
                    <author authorORCID="0000-0002-1492-9481" order="8">Degtjarik O</author>
                    <author order="9">Musgrove LJ</author>
                    <author authorORCID="0000-0003-2437-7761" order="10">Calabrese AN</author>
                    <author authorORCID="0000-0003-0239-5926" order="11">Zeqiraj E</author>
                    <author authorORCID="0000-0003-1326-8981" order="12">Greenberg RA</author>
                    <title>The SPATA5-SPATA5L1 ATPase complex directs replisome proteostasis to ensure genome integrity</title>
                    <journal>Cell</journal>
                    <journalAbbreviation>Cell</journalAbbreviation>
                    <country></country>
                    <issue>187</issue>
                    <volume>9</volume>
                    <firstPage>2250</firstPage>
                    <lastPage>2268</lastPage>
                    <year>2024</year>
                    <language>English</language>
                    <externalReferences type="doi">10.1016/j.cell.2024.03.002</externalReferences>
                    <externalReferences type="pubmed">38554706</externalReferences>
                    <details>N/A</details>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>Unaligned multiframe micrographs in the EER format of the 55LCC ATPase complex</name>
        <directory>/data/20230605_RawData</directory>
        <category>micrographs - multiframe</category>
        <headerFormat>EER</headerFormat>
        <dataFormat>EER</dataFormat>
        <numImagesOrTiltSeries>27595</numImagesOrTiltSeries>
        <framesPerImage>918</framesPerImage>
        <voxelType>UNSIGNED 16 BIT INTEGER</voxelType>
        <dimensions>
            <imageWidth>variable</imageWidth>
            <pixelWidth>0.74</pixelWidth>
            <imageHeight>variable</imageHeight>
            <pixelHeight>0.74</pixelHeight>
        </dimensions>
        <details>A dose per physical pixel/s of 6.88 was used, resulting in a total electron dose of 37.6 e-/Å2, fractionated across 918 EPU frames. These were then grouped into 20 frames, resulting in an electron dose of 0.8 e-/Å2 per frame.</details>
        <segmentationList/>
        <micrographsFilePattern>data/20230605_RawData/Images-Disc1/GridSquare_*/Data/*.eer</micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
    <imageSet>
        <name>Aligned micrographs of of the 55LCC ATPase complex</name>
        <directory>/data/Raw_data</directory>
        <category>micrographs - single frame</category>
        <headerFormat>MRC</headerFormat>
        <dataFormat>MRC</dataFormat>
        <numImagesOrTiltSeries>27595</numImagesOrTiltSeries>
        <framesPerImage>1</framesPerImage>
        <voxelType>32 BIT FLOAT</voxelType>
        <dimensions>
            <imageWidth>variable</imageWidth>
            <pixelWidth>0.74</pixelWidth>
            <imageHeight>variable</imageHeight>
            <pixelHeight>0.74</pixelHeight>
        </dimensions>
        <details>Raw movie frames are aligned with RELION's own implementation of the MotionCor2 algorithm using an EER fractionation of 47.</details>
        <segmentationList/>
        <micrographsFilePattern>data/Raw_data/*.mrc</micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
</entry>
