REL
2024-09-03
2024-12-03
2024-12-03
Full-length mouse 5-HT3A receptor in complex with serotonin, pre-activated and open-like
0000-0002-1832-747X
Kevin
Christopher
Felt
Department of Physiology and Biophysics, Case Western Reserve University
10900 Euclid Ave
Cleveland
Ohio
United States
44106
Sudha
Chakrapani
Case Western Reserve University, Department of Pharmacology
10900 Euclid Ave
Cleveland
Ohio
United States
44106
Felt KCF
Chakrapani SC
National Institutes of Health (NIH)
R01GM131216
United States
2.7
10.6019/EMPIAR-12265
EMDB
molecule
EMD-29411
EMD-29418
Felt K
Stauffer M
Salas-Estrada L
Guzzo PR
Xie D
Huang J
Filizola M
Chakrapani S
Structural basis for partial agonism in 5-HT<sub>3A</sub> receptors
Nature structural & molecular biology
Nat Struct Mol Biol
United States
4
31
598
609
2024
English
10.1038/s41594-023-01140-2
38177669
Raw movies, 5-HT3A + serotonin
/data/Micrographs
micrographs - multiframe
TIFF
TIFF
5771
40
UNSIGNED BYTE
11520
1.1
8184
1.1
Raw movies of 5-HT3AR in complex with 100uM serotonin. Collected on titan krios and k3 camera. 81,000x magnification, super-resolution (import with 0.55 angstrom pixel size, 2x bin in Motioncorr), around 1 electron dose per frame. Dataset 1 of 2.
data/Micrographs/FoilHole_2660756_Data_2658853_2658855_20210603_111614_fractions.tiff