REL 2024-04-17 2024-08-26 2024-08-27 Single particle cryo-EM analysis of inhibitor 172 bound cystic fibrosis transmembrane conductance regulator E1371Q mutant 0000-0001-8933-9286 Xiaolong Gao University of Missouri-Columbia Columbia Missouri United States 65211 0000-0001-8933-9286 Xiaolong Gao University of Missouri-Columbia Columbia Missouri United States 65211 Tzyh-Chang Hwang University of Missouri-Columbia Columbia Missouri United States 65211 Gao X Hwang T 6.4 10.6019/EMPIAR-12044 EMDB molecule EMD-43014 Gao X Yeh HI Yang Z Fan C Jiang F Howard RJ Lindahl E Kappes JC Hwang TC Allosteric inhibition of CFTR gating by CFTRinh-172 binding in the pore Nature communications Nat Commun 1 15 2024 English 10.1038/s41467-024-50641-1 39107303 Unaligned multi-frame micrographs of inhibitor 172 bound human cystic fibrosis transmembrane conductance regulator E1371Q mutant /data/Movies micrographs - multiframe TIFF TIFF 10700 50 UNSIGNED BYTE 11520 variable 8184 variable