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2024-03-08
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2024-03-20
Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex
0000-0002-3664-0072
Theodore
Jardetzky
Department of Structural Biology, Stanford University School of Medicine
Stanford
United States
94305
0000-0002-3664-0072
Theodore
Jardetzky
Department of Structural Biology, Stanford University School of Medicine
Stanford
United States
94305
0000-0003-0238-7846
Georgios
Skiniotis
Department of Molecular and Cellular Physiology, Stanford University School of Medicine
Stanford
United States
94305
0000-0001-8746-3339
Alexander
Eggel
Department of Rheumatology and Immunology, University Hospital Bern
Bern
Switzerland
3012
Pennington LF
Gasser P
Kleinboelting S
Zhang C
Skiniotis G
Eggel A
Jardetzky TS
National Institutes of Health (NIH)
AI120510
United States
National Institutes of Health (NIH)
AI115469
United States
National Institutes of Health (NIH)
HL141493
United States
52.0
10.6019/EMPIAR-11954
EMDB
molecule
EMD-25136
Pennington LF
Gasser P
Kleinboelting S
Zhang C
Skiniotis G
Eggel A
Jardetzky TS
Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex
Nature communications
Nat Commun
1
12
2021
English
10.1038/s41467-021-27397-z
34862384
clone 7-scFv2:IgE-Fc2–4(G335C):FcεRIα(W156C) complex
/data
micrographs - single frame
MRC
MRC
592
1
32 BIT FLOAT
5760
0.8521
4092
0.8521