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    <admin>
        <currentStatus>REL</currentStatus>
        <keyDates>
            <depositionDate>2024-03-02</depositionDate>
            <releaseDate>2025-02-10</releaseDate>
            <updateDate>2025-03-17</updateDate>
        </keyDates>
        <title>Cryo electron structure of the ectodomain of Site-one protease without SPRING</title>
        <correspondingAuthor private="true">
            <authorORCID>0000-0001-8657-9348</authorORCID>
            <firstName>Daniel</firstName>
            <middleName>L</middleName>
            <lastName>Kober</lastName>
            <organization type="academic">University of Texas Southwestern Medical Center</organization>
            <street>5323 Harry Hines Blvd</street>
            <townOrCity>Dallas</townOrCity>
            <stateOrProvince>TX</stateOrProvince>
            <country>United States</country>
            <postOrZipCode>75390</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator private="true">
            <authorORCID>0000-0001-8657-9348</authorORCID>
            <firstName>Daniel</firstName>
            <lastName>Kober</lastName>
            <organization type="academic">Department of Biochemistry, University of Texas Southwestern Medical Center</organization>
            <street>5323 Harry Hines Blvd</street>
            <townOrCity>Dallas</townOrCity>
            <stateOrProvince>Texas</stateOrProvince>
            <country>United States</country>
            <postOrZipCode>75390</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author authorORCID="0000-0001-8657-9348">Kober DL</author>
        </authorsList>
        <grantSupport>
            <grantReference>
                <fundingBody>National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)</fundingBody>
                <code>R00GM141261</code>
                <country>United States</country>
            </grantReference>
            <grantReference>
                <fundingBody>Cancer Prevention and Research Institute of Texas (CPRIT)</fundingBody>
                <code>CPRIT RP22052</code>
                <country>United States</country>
            </grantReference>
        </grantSupport>
        <datasetSize units="TB">3.1</datasetSize>
        <entryDOI>10.6019/EMPIAR-11931</entryDOI>
        <experimentType>EMDB</experimentType>
        <scale>molecule</scale>
    </admin>
    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-42661</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="false">
                    <author authorORCID="0000-0003-2055-9883" order="1">Hendrix S</author>
                    <author authorORCID="0009-0009-5146-0596" order="2">Dartigue V</author>
                    <author order="3">Hall H</author>
                    <author authorORCID="0000-0002-0785-3044" order="4">Bawaria S</author>
                    <author authorORCID="0000-0003-2822-5415" order="5">Kingma J</author>
                    <author order="6">Bajaj B</author>
                    <author authorORCID="0000-0001-6935-7532" order="7">Zelcer N</author>
                    <author authorORCID="0000-0001-8657-9348" order="8">Kober DL</author>
                    <title>SPRING licenses S1P-mediated cleavage of SREBP2 by displacing an inhibitory pro-domain</title>
                    <journal>Nature communications</journal>
                    <journalAbbreviation>Nat Commun</journalAbbreviation>
                    <country></country>
                    <issue>1</issue>
                    <volume>15</volume>
                    <year>2024</year>
                    <language>English</language>
                    <externalReferences type="doi">10.1038/s41467-024-50068-8</externalReferences>
                    <externalReferences type="pubmed">38977690</externalReferences>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>eer format movies of site-one protease</name>
        <directory>/data/movies</directory>
        <category>micrographs - multiframe</category>
        <headerFormat>EER</headerFormat>
        <dataFormat>EER</dataFormat>
        <numImagesOrTiltSeries>6171</numImagesOrTiltSeries>
        <framesPerImage>1</framesPerImage>
        <frameRange>
            <frameRangeMin>1</frameRangeMin>
            <frameRangeMax>1112</frameRangeMax>
        </frameRange>
        <voxelType>32 BIT FLOAT</voxelType>
        <dimensions>
            <imageWidth>4096</imageWidth>
            <pixelWidth>0.738</pixelWidth>
            <imageHeight>4096</imageHeight>
            <pixelHeight>0.738</pixelHeight>
        </dimensions>
        <details>Unprocessed micrographs and gain ref file for data collection corresponding to EMD-42661. The pixel size was 0.738 A. The nominal dose rate was 8.5 eps and the total dose was 55 e/A2. For processing, the movies were split into 50 frames.</details>
        <segmentationList/>
        <micrographsFilePattern>data/movies/20230918_127*.eer</micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
</entry>
