<entry xmlns="http://pdbe.org/empiar" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="https://ftp.ebi.ac.uk/pub/databases/emtest/empiar/schema/empiar.xsd" accessionCode="EMPIAR-11822" schemaVersion="0.65" public="true">
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        <keyDates>
            <depositionDate>2023-12-01</depositionDate>
            <releaseDate>2024-06-05</releaseDate>
            <updateDate>2024-06-05</updateDate>
        </keyDates>
        <title>Native structure of a human GBP defense complex for cell-autonomous immunity to infection</title>
        <correspondingAuthor private="true">
            <authorORCID>0000-0002-1734-135X</authorORCID>
            <firstName>John</firstName>
            <middleName>David</middleName>
            <lastName>MacMicking</lastName>
            <organization type="academic">Howard Hughes Medical Institute - Yale University School of Medicine</organization>
            <townOrCity>West haven</townOrCity>
            <stateOrProvince>Connecticut</stateOrProvince>
            <country>United States</country>
            <postOrZipCode>06516</postOrZipCode>
        </correspondingAuthor>
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            <firstName>John</firstName>
            <middleName>David</middleName>
            <lastName>MacMicking</lastName>
            <organization type="academic">Howard Hughes Medical Institute - Yale University School of Medicine</organization>
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            <stateOrProvince>Connecticut</stateOrProvince>
            <country>United States</country>
            <postOrZipCode>06516</postOrZipCode>
        </principalInvestigator>
        <principalInvestigator private="true">
            <authorORCID>0000-0003-1145-1192</authorORCID>
            <firstName>Shiwei</firstName>
            <lastName>Zhu</lastName>
            <organization type="academic">Case Western Reserve University</organization>
            <street>2109 Adelbert Rd, Robbins E621</street>
            <townOrCity>Cleveland</townOrCity>
            <stateOrProvince>Ohio</stateOrProvince>
            <country>United States</country>
            <postOrZipCode>44106</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author authorORCID="0000-0002-1734-135X">MacMicking JDM</author>
            <author authorORCID="0000-0003-1145-1192">Zhu SZ</author>
        </authorsList>
        <grantSupport>
            <grantReference>
                <fundingBody>National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)</fundingBody>
                <code>R01AI068041-14, R01AI108834-07</code>
                <country>United States</country>
            </grantReference>
        </grantSupport>
        <datasetSize units="GB">9.7</datasetSize>
        <entryDOI>10.6019/EMPIAR-11822</entryDOI>
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        <scale>cell</scale>
    </admin>
    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-43091</emdbEntry>
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        <citationList>
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                <journalCitation published="true" preprint="false">
                    <author authorORCID="0000-0003-1145-1192" order="1">Zhu S</author>
                    <author authorORCID="0000-0001-6410-3517" order="2">Bradfield CJ</author>
                    <author authorORCID="0000-0002-1300-8242" order="3">Maminska A</author>
                    <author authorORCID="0000-0002-1375-8027" order="4">Park ES</author>
                    <author authorORCID="0000-0001-6866-7248" order="5">Kim BH</author>
                    <author order="6">Kumar P</author>
                    <author authorORCID="0000-0002-8903-122X" order="7">Huang S</author>
                    <author order="8">Kim M</author>
                    <author authorORCID="0000-0002-4569-8137" order="9">Zhang Y</author>
                    <author authorORCID="0000-0002-4085-7020" order="10">Bewersdorf J</author>
                    <author authorORCID="0000-0002-1734-135X" order="11">MacMicking JD</author>
                    <title>Native architecture of a human GBP1 defense complex for cell-autonomous immunity to infection</title>
                    <journal>Science (New York, N.Y.)</journal>
                    <journalAbbreviation>Science</journalAbbreviation>
                    <country></country>
                    <issue>6686</issue>
                    <volume>383</volume>
                    <year>2024</year>
                    <language>English</language>
                    <externalReferences type="doi">10.1126/science.abm9903</externalReferences>
                    <externalReferences type="pubmed">38422126</externalReferences>
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                <journalCitation published="true" preprint="true">
                    <author order="1">Zhu S</author>
                    <author order="2">Bradfield CJ</author>
                    <author order="3">Mamińska A</author>
                    <author order="4">Park E</author>
                    <author authorORCID="0000-0001-6866-7248" order="5">Kim B</author>
                    <author order="6">Kumar P</author>
                    <author authorORCID="0000-0002-8903-122X" order="7">Huang S</author>
                    <author order="8">Zhang Y</author>
                    <author authorORCID="0000-0002-4085-7020" order="9">Bewersdorf J</author>
                    <author authorORCID="0000-0002-1734-135X" order="10">MacMicking JD</author>
                    <title>Cryo-ET of a human GBP coatomer governing cell-autonomous innate immunity to infection</title>
                    <journal>bioRxiv</journal>
                    <journalAbbreviation></journalAbbreviation>
                    <country></country>
                    <year>2021</year>
                    <externalReferences type="doi">10.1101/2021.08.26.457804</externalReferences>
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            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>Human GBP1 on Salmonella minicell surface</name>
        <directory>/data</directory>
        <category>tilt series</category>
        <headerFormat>TIFF</headerFormat>
        <dataFormat>TIFF</dataFormat>
        <numImagesOrTiltSeries>280</numImagesOrTiltSeries>
        <framesPerImage>5</framesPerImage>
        <voxelType>SIGNED BYTE</voxelType>
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            <imageWidth>11520</imageWidth>
            <pixelWidth>0.693</pixelWidth>
            <imageHeight>8184</imageHeight>
            <pixelHeight>0.693</pixelHeight>
        </dimensions>
        <details>Images were collected at SuperResolution mode</details>
        <segmentationList/>
        <micrographsFilePattern></micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
</entry>
