REL
2023-11-27
2024-09-03
2024-09-03
AL amyloid fibril from the FOR103 light chain
0000-0002-9442-460X
Matthias
Schmidt
Institut für Proteinbiochemie, Universität Ulm
8/1 Helmholtzstrasse
Ulm
Baden Württemberg
Germany
89081
0000-0003-2123-6816
Marcus
Fändrich
Institut für Proteinbiochemie, Universität Ulm
8/1 Helmholtzstrasse
Ulm
Baden Württemberg
Germany
89081
Pfeiffer PB
Karimi-Farsijani S
Schmidt M
Fändrich M
German Research Foundation (DFG)
FA 456/23
Germany
504.3
10.6019/EMPIAR-11801
EMDB
molecule
EMD-19818
Karimi-Farsijani S
Pfeiffer PB
Banerjee S
Baur J
Kuhn L
Kupfer N
Hegenbart U
Schönland SO
Wiese S
Haupt C
Schmidt M
Fändrich M
Light chain mutations contribute to defining the fibril morphology in systemic AL amyloidosis
Unaligned multi-frame micrographs of FOR103 amyloid fibrils
/data/micrographs
micrographs - multiframe
TIFF
TIFF
2788
40
UNSIGNED 16 BIT INTEGER
3838
1.04
3710
1.04
Krios1 Quantum-K2
Cs 2.7
300kV EFTEM nanpprobe
x130k spot 8 beam size 650nm
c2=50 objective_aperture=100
GIF-K2 counting
10s exposure 40 frames
total dose at the sample 53.70e/A2
1 pixel = 1.04A
dose rate ~3-4 e/pix/s
defocus range -1.2 to -2.5
The gain reference (/data/micrographs/CountRef_map_0076_001.dm4) is not applied to the micrographs. The NOTES.txt file contains EM information. Thumbnails and power spectra (data/thumbs) as well as coordinates (/data/Manual_Pick) are provided.
data/micrographs/*.tif
data/Manual_Pick/*.star
data/Manual_Pick