REL 2023-11-10 2024-02-06 2024-02-06 SpCas9 bound to 18 nucleotide complementary DNA substrate in the checkpoint state 0000-0002-7601-210X Martin Jinek Department of Biochemistry, University of Zurich Winterthurerstrasse 190 Zurich ZH Switzerland 8057 0000-0002-7601-210X Martin Jinek Department of Biochemistry, University of Zurich Winterthurerstrasse 190 Zurich ZH Switzerland 8057 Pacesa M Loeff L Querques I Muckenfuss LM Sawicka M Jinek M Swiss National Science Foundation 31003A_182567 Switzerland 7.7 10.6019/EMPIAR-11784 EMDB molecule EMD-14501 Pacesa M Loeff L Querques I Muckenfuss LM Sawicka M Jinek M R-loop formation and conformational activation mechanisms of Cas9 Nature Nature 7925 609 191 196 2022 English 10.1038/s41586-022-05114-0 36002571 Unaligned multi-frame micrographs of SpCas9 bound to 18 nucleotide complementary DNA substrate in checkpoint state /data/Images-Disc1/GridSquare_6172515/Data micrographs - multiframe EER EER 8541 532 1 532 32 BIT FLOAT 4096 0.45 4096 0.45
Unaligned multi-frame movies with each containing 532 frames per movie collected at 300 kV on FALCON 4 detector. Total accumulated electron exposure on the specimen level corresponds to 132.9 electrons per Å^2.
data/Images-Disc1/GridSquare_6172515/Data/*EER.eer Unaligned multi-frame micrographs of SpCas9 bound to 18 nucleotide complementary DNA substrate in checkpoint state /data/Images-Disc1/GridSquare_6172543/Data micrographs - multiframe EER EER 8199 532 1 532 32 BIT FLOAT 4096 0.45 4096 0.45
Unaligned multi-frame movies with each containing 532 frames per movie collected at 300 kV on FALCON 4 detector. Total accumulated electron exposure on the specimen level corresponds to 132.9 electrons per Å^2.
data/Images-Disc1/GridSquare_6172543/Data/*_EER.eer Unaligned multi-frame micrographs of SpCas9 bound to 18 nucleotide complementary DNA substrate in checkpoint state /data/Images-Disc1/GridSquare_6172599/Data micrographs - multiframe EER EER 7344 532 1 532 32 BIT FLOAT 4096 0.45 4096 0.45
Unaligned multi-frame movies with each containing 532 frames per movie collected at 300 kV on FALCON 4 detector. Total accumulated electron exposure on the specimen level corresponds to 132.9 electrons per Å^2.
data/Images-Disc1/GridSquare_6172599/Data/FoilHole_*_EER.eer Unaligned multi-frame micrographs of SpCas9 bound to 18 nucleotide complementary DNA substrate in checkpoint state /data/Images-Disc1/GridSquare_6172602/Data micrographs - multiframe EER EER 7890 532 1 532 32 BIT FLOAT 4096 0.45 4096 0.45
Unaligned multi-frame movies with each containing 532 frames per movie collected at 300 kV on FALCON 4 detector. Total accumulated electron exposure on the specimen level corresponds to 132.9 electrons per Å^2.
data/Images-Disc1/GridSquare_6172602/Data/*_EER.eer Unaligned multi-frame micrographs of SpCas9 bound to 18 nucleotide complementary DNA substrate in checkpoint state /data/Images-Disc1/GridSquare_6172642/Data micrographs - multiframe EER EER 8541 532 1 532 32 BIT FLOAT 4096 0.45 4096 0.45
Unaligned multi-frame movies with each containing 532 frames per movie collected at 300 kV on FALCON 4 detector. Total accumulated electron exposure on the specimen level corresponds to 132.9 electrons per Å^2.
data/Images-Disc1/GridSquare_6172642/Data/*EER.eer