REL
2023-10-12
2024-09-03
2024-09-03
ATTRG47E amyloid fibrils from hereditary ATTR amloidosis
0000-0002-9442-460X
Matthias
Schmidt
Institut für Proteinbiochemie, Universität Ulm
8/1 Helmholtzstrasse
Ulm
Baden Württemberg
Germany
89081
0000-0003-2123-6816
Marcus
Fändrich
Institut für Proteinbiochemie, Universität Ulm
8/1 Helmholtzstrasse
Ulm
Baden Württemberg
Germany
89081
Steinebrei M
Schmidt M
Fändrich M
German Research Foundation (DFG)
FA 456/28
Germany
6.8
10.6019/EMPIAR-11730
EMDB
molecule
EMD-17737
Steinebrei M
Baur J
Pradhan A
Kupfer N
Wiese S
Hegenbart U
Schönland SO
Schmidt M
Fändrich M
Common transthyretin-derived amyloid fibril structures in patients with hereditary ATTR amyloidosis
Nature communications
Nat Commun
1
14
2023
English
10.1038/s41467-023-43301-3
37993462
Unaligned multi-frame micrographs of ATTRVG47E amyloid fibrils
/data/Micrographs_raw_G47E
micrographs - multiframe
EER
EER
12067
2226
UNSIGNED BYTE
4096
0.934
4096
0.934
EMBL Heidelberg (25 November 2021)
IC-Krios1 300kV Cold FEG
SelectrisX Falcon4 10eV slit
Cs=2.7mm, C2aperture=50um, ObjAperture=100um
EFTEM 130K, nanoprobe spot 5, beam=650nm
Counting mode, 1pix=0.934A
9s exposure, EER files saved (2226 raw EER frames)
dose rate ~4e/pix/s at the sample level (~41.63 e/A2 total!)
4 shots per hole, no middle
defocus range -0.90 to -1.80um
data/Micrographs_raw_G47E
data/ManualPick_G47E/20211125_Ulm_VID30247/11-A_001_manualpick.star
data/ManualPick_G47E