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        <keyDates>
            <depositionDate>2023-06-26</depositionDate>
            <releaseDate>2024-01-05</releaseDate>
            <updateDate>2024-01-05</updateDate>
        </keyDates>
        <title>ATTRV20I amyloid fibrils from hereditary ATTR amloidosis</title>
        <correspondingAuthor private="true">
            <authorORCID>0000-0002-9442-460X</authorORCID>
            <firstName>Matthias</firstName>
            <lastName>Schmidt</lastName>
            <organization type="academic">Institut für Proteinbiochemie, Universität Ulm</organization>
            <street>8/1 Helmholtzstrasse</street>
            <townOrCity>Ulm</townOrCity>
            <stateOrProvince>Baden Württemberg</stateOrProvince>
            <country>Germany</country>
            <postOrZipCode>89081</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator private="true">
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            <firstName>Marcus</firstName>
            <lastName>Fändrich</lastName>
            <organization type="academic">Institut für Proteinbiochemie, Universität Ulm</organization>
            <street>8/1 Helmholtzstrasse</street>
            <townOrCity>Ulm</townOrCity>
            <stateOrProvince>Baden Württemberg</stateOrProvince>
            <country>Germany</country>
            <postOrZipCode>89081</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author authorORCID="0000-0002-0582-3909">Steinebrei M</author>
            <author authorORCID="0000-0002-9442-460X">Schmidt M</author>
            <author authorORCID="0000-0003-2123-6816">Fändrich M</author>
        </authorsList>
        <grantSupport>
            <grantReference>
                <fundingBody>German Research Foundation (DFG)</fundingBody>
                <code>FA 456/28</code>
                <country>Germany</country>
            </grantReference>
        </grantSupport>
        <datasetSize units="TB">1.2</datasetSize>
        <entryDOI>10.6019/EMPIAR-11700</entryDOI>
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        <scale>molecule</scale>
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    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-17736</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
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                <journalCitation published="true" preprint="false">
                    <author authorORCID="0000-0002-0582-3909" order="1">Steinebrei M</author>
                    <author order="2">Baur J</author>
                    <author order="3">Pradhan A</author>
                    <author order="4">Kupfer N</author>
                    <author authorORCID="0000-0001-5697-2608" order="5">Wiese S</author>
                    <author authorORCID="0000-0003-1917-6746" order="6">Hegenbart U</author>
                    <author authorORCID="0000-0002-4853-5579" order="7">Schönland SO</author>
                    <author authorORCID="0000-0002-9442-460X" order="8">Schmidt M</author>
                    <author authorORCID="0000-0003-2123-6816" order="9">Fändrich M</author>
                    <title>Common transthyretin-derived amyloid fibril structures in patients with hereditary ATTR amyloidosis</title>
                    <journal>Nature communications</journal>
                    <journalAbbreviation>Nat Commun</journalAbbreviation>
                    <country></country>
                    <issue>1</issue>
                    <volume>14</volume>
                    <year>2023</year>
                    <language>English</language>
                    <externalReferences type="doi">10.1038/s41467-023-43301-3</externalReferences>
                    <externalReferences type="pubmed">37993462</externalReferences>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>Unaligned multi-frame micrographs of ATTRV20I amyloid fibrils</name>
        <directory>/data/PKG - data_November2021/data</directory>
        <category>micrographs - multiframe</category>
        <headerFormat>TIFF</headerFormat>
        <dataFormat>TIFF</dataFormat>
        <numImagesOrTiltSeries>3954</numImagesOrTiltSeries>
        <framesPerImage>40</framesPerImage>
        <voxelType>UNSIGNED BYTE</voxelType>
        <dimensions>
            <imageWidth>5760</imageWidth>
            <pixelWidth>0.822</pixelWidth>
            <imageHeight>4092</imageHeight>
            <pixelHeight>0.822</pixelHeight>
        </dimensions>
        <details>Krios2 300kV Quantum-K3
Cs = 2.7mm, C2 aperture = 50um, Obj aperture = 100um
EFTEM 105K, nanoprobe spot 7, beam = 650nm
Counting mode, 1 pix = 0.822A
1.2s exposure, 40 frames saved
40.33 e/A2 total
camera dose rate = ~15 e/pix/s</details>
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