REL 2022-12-06 2023-04-11 2023-04-11 Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism 0000-0002-4011-8308 Christopher G Bunick Department of Dermatalogy, Yale School of Medicine 266 Whitney Avenue New Haven Connecticut United States 06511 0000-0002-4011-8308 Christopher Bunick Department of Dermatology, Yale School of Medicine 266 Whitney Avenue New Haven Connecticut United States 06511 Lomakin IB Devarkar SC Patel S Grada A Bunick CG 6.2 10.6019/EMPIAR-11362 EMDB molecule EMD-26959 Lomakin IB Devarkar SC Patel S Grada A Bunick CG Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism Nucleic acids research Nucleic Acids Res 2023 English 10.1093/nar/gkad103 36864821 Raw multiframe micrographs for Sarecycline bound 70S Ribosome from C. acnes /data/rawTIF Movies micrographs - multiframe TIFF TIFF 10765 35 UNSIGNED BYTE 11520 0.534 8184 0.534
Extracted particle stack based on Template picking from cryoSPARC /data/ParticleStack picked particles - single frame - processed MRC MRC 1108852 1 32 BIT FLOAT 340 1.068 340 1.068
A stack of 1108852 particles picked from 10,765 motion-corrected micrographs
 Dose-Weighted Motion Corrected Micrographs for Sarecycline bound 70S Ribosome from C. acnes /data/MotionCorrected_Micrographs micrographs - single frame MRC MRC 10765 35 32 BIT FLOAT 5760 1.068 4092 1.068
Dose-weighted motion corrected micrographs using Patch motion correction in cryoSPARC
data/MotionCorrected_Micrographs/*_slot12_*_patch_aligned_doseweighted.mrc Non-Dose-Weighted Motion Corrected Micrographs for Sarecycline bound 70S Ribosome from C. acnes /data/MotionCorrected_Micrographs/Non-Doseweighted micrographs - single frame MRC MRC 10765 35 32 BIT FLOAT 5760 1.068 4092 1.068
Non-dose-weighted motion corrected micrographs using Patch motion correction in cryoSPARC
data/MotionCorrected_Micrographs/Non-Doseweighted/*_slot12_*_patch_aligned.mrc