Amyloid fibril structure from the vascular variant of systemic AA amyloidosis

REL 2022-12-05 2022-12-16 2022-12-16 Amyloid fibril structure from the vascular variant of systemic AA amyloidosis 0000-0002-9442-460X Matthias Schmidt Institut für Proteinbiochemie, Universität Ulm 8/1 Helmholtzstrasse Ulm Baden Württemberg Germany 89081 0000-0003-2123-6816 Marcus Fändrich Institut für Proteinbiochemie, Universität Ulm 8/1 Helmholtzstrasse Ulm Baden Württemberg Germany 89081 Banerjee S Baur J Daniel C Pfeiffer PB Hitzenberger M Kuhn L Wiese S Bijzet J Haupt C Amann KU Zacharias M Hazenberg BPC Westermark GT Schmidt M Fändrich M 1009.8 10.6019/EMPIAR-11342 EMDB molecule EMD-14771 Banerjee S Baur J Daniel C Pfeiffer PB Hitzenberger M Kuhn L Wiese S Bijzet J Haupt C Amann KU Zacharias M Hazenberg BPC Westermark GT Schmidt M Fändrich M Schmidt M Amyloid fibril structure from the vascular variant of systemic AA amyloidosis Nature communications Nat Commun 1 13 7261 7268 2022 English 10.1038/s41467-022-34636-4 36433936

Raw micrographs were collected with TEM accelerated at 300kV and equipped with a direct electron detector. The micrographs constitute 40 frames with a pixel size of 1.04 A.

Unaligned ultiframe micrographs of ex vivo human vascular AA amyloidosis -patient I /data/vascular variant patient I micrographs - multiframe TIFF TIFF 1955 40 UNSIGNED 16 BIT INTEGER 3838 1.04 3710 1.04

Data collection with Titan Krios EM(300kV) using K2 camera. Other details can be obtained from NOTES file in the dataset directory

data/vascular variant patient I/rawdata Unaligned ultiframe micrographs of ex vivo human vascular AA amyloidosis -patient II /data/vascular variant patient II micrographs - multiframe TIFF TIFF 3350 40 UNSIGNED 16 BIT INTEGER 3838 1.04 3710 1.04

Data collection with Titan Krios EM(300kV) using K2 camera. Other details can be obtained from NOTES file in the dataset directory

data/vascular variant patient II/data