<entry xmlns="http://pdbe.org/empiar" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="https://ftp.ebi.ac.uk/pub/databases/emtest/empiar/schema/empiar.xsd" accessionCode="EMPIAR-11255" public="true">
    <admin>
        <currentStatus>REL</currentStatus>
        <keyDates>
            <depositionDate>2022-02-02</depositionDate>
            <releaseDate>2022-11-01</releaseDate>
            <updateDate>2022-11-01</updateDate>
        </keyDates>
        <title>Cryo-EM movies of the human α1β3γ2 GABA&lt;sub&gt;A&lt;/sub&gt; receptor in a lipid bilayer</title>
        <correspondingAuthor>
            <authorORCID>0000-0003-3783-1388</authorORCID>
            <firstName>Alexandru</firstName>
            <middleName>Radu</middleName>
            <lastName>Aricescu</lastName>
            <organization type="academic">MRC Laboratory of Molecular Biology</organization>
            <street>Francis Crick Avenue</street>
            <townOrCity>Cambridge</townOrCity>
            <stateOrProvince>Cambridgeshire</stateOrProvince>
            <country>United Kingdom</country>
            <postOrZipCode>CB2 0QH</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator>
            <authorORCID>0000-0003-3783-1388</authorORCID>
            <firstName>Alexandru</firstName>
            <middleName>Radu</middleName>
            <lastName>Aricescu</lastName>
            <organization type="academic">MRC Laboratory of Molecular Biology</organization>
            <street>Francis Crick Avenue</street>
            <townOrCity>Cambridge</townOrCity>
            <stateOrProvince>Cambridgeshire</stateOrProvince>
            <country>United Kingdom</country>
            <postOrZipCode>CB2 0QH</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author>Laverty D</author>
            <author authorORCID="0000-0001-8986-913X">Masiulis S</author>
            <author authorORCID="0000-0003-3783-1388">Aricescu AR</author>
        </authorsList>
        <datasetSize>1007.4</datasetSize>
        <entryDOI>10.6019/EMPIAR-11255</entryDOI>
        <experimentType>EMDB</experimentType>
        <scale>molecule</scale>
    </admin>
    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-4411</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="false">
                    <author order="1">Laverty D</author>
                    <author authorORCID="0000-0003-1270-7188" order="2">Desai R</author>
                    <author authorORCID="0000-0001-8456-4206" order="3">Uchański T</author>
                    <author authorORCID="0000-0001-8986-913X" order="4">Masiulis S</author>
                    <author order="5">Stec WJ</author>
                    <author authorORCID="0000-0002-4847-5529" order="6">Malinauskas T</author>
                    <author authorORCID="0000-0001-8407-0759" order="7">Zivanov J</author>
                    <author authorORCID="0000-0002-2466-0172" order="8">Pardon E</author>
                    <author authorORCID="0000-0002-3825-874X" order="9">Steyaert J</author>
                    <author authorORCID="0000-0001-5718-3782" order="10">Miller KW</author>
                    <author authorORCID="0000-0003-3783-1388" order="11">Aricescu AR</author>
                    <title>Cryo-EM structure of the human α1β3γ2 GABA&lt;sub&gt;A&lt;/sub&gt; receptor in a lipid bilayer</title>
                    <journal>Nature</journal>
                    <journalAbbreviation>Nature</journalAbbreviation>
                    <country>United Kingdom</country>
                    <issue>7740</issue>
                    <volume>565</volume>
                    <firstPage>516</firstPage>
                    <lastPage>520</lastPage>
                    <year>2019</year>
                    <language>English</language>
                    <externalReferences type="doi">10.1038/s41586-018-0833-4</externalReferences>
                    <externalReferences type="pubmed">30602789</externalReferences>
                    <details>Raw movies from Falcon 3 detector in electron-counting mode at a nominal magnification of 75,000, corresponding to a calibrated pixel size of 1.07 Å. Each micrograph was collected as a 60-s exposure, comprising 75 movie frames at a dose rate of 0.55 electrons per pixel per second for a total accumulated dose of 30.84 e/A2 with a Volta Phase Plate.</details>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>Cryo-EM movies of the human α1β3γ2 GABAA receptor in a lipid bilayer</name>
        <directory>/data</directory>
        <category>micrographs - multiframe</category>
        <headerFormat>TIFF</headerFormat>
        <dataFormat>TIFF</dataFormat>
        <numImagesOrTiltSeries>790</numImagesOrTiltSeries>
        <framesPerImage>75</framesPerImage>
        <frameRange>
            <frameRangeMin>1</frameRangeMin>
            <frameRangeMax>75</frameRangeMax>
        </frameRange>
        <voxelType>SIGNED 16 BIT INTEGER</voxelType>
        <dimensions>
            <imageWidth>4096</imageWidth>
            <pixelWidth>1.07</pixelWidth>
            <imageHeight>4096</imageHeight>
            <pixelHeight>1.07</pixelHeight>
        </dimensions>
        <details></details>
        <segmentationList/>
        <micrographsFilePattern></micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
</entry>
