REL 2022-06-01 2023-03-15 2023-03-15 Performing Correlative Light and Electron Microscopy to reveal the structural organization and location of alpha-synuclein aggregation hotspots inside the neuron. Catherine Maclachlan The Francis Crick Institute London United Kingdom NW1 1AT Catherine Maclachlan The Francis Crick Institute London United Kingdom NW1 1AT Minee Choi The Francis Crick Institute London United Kingdom NW1 1ST Sonia Ghandi The Francis Crick Institute London United Kingdom NW1 1ST Lucy Collinson The Francis Crick Institute London United Kingdom NW1 1ST Choi ML Chappard A Singh BP Maclachlan C Rodrigues M Fedotova E Berezhnov AV De S Peddie C Athauda D Viridi GS Zhang W Evans JR Wernick A Zanjani ZS Angelova PR Esteras N Vinikurov A Morris K Jeacock K Tosatto L Little D Gissen P Collinson L Clarke DJ Kunath T Klenerman D Abramov AY Horrocks MH Gandhi S 88.4 10.6019/EMPIAR-11066 CLEM cell Choi ML Chappard A Singh BP Maclachlan C Rodrigues M Fedotova E Berezhnov AV De S Peddie C Athauda D Virdi GS Zhang W Evans JR Wernick A Zanjani ZS Angelova PR Esteras N Vinikurov A Morris K Jeacock K Tosatto L Little D Gissen P Clarke DJ Kunath T Collinson L Klenerman D Abramov AY Horrocks MH Gandhi S Structural conversion of α-synuclein at the mitochondria induces neuronal toxicity bioRxiv 2022 10.1101/2022.06.07.494932
All the Electron Microscopy images associated with samples mentioned in the publication. Images come from two sources. TEM images and FIBSEM.
 S-BIAD465 Unaligned TEM serial imaging data of a neuronal cell in culture (dish41) /data/Electron_Microscopy/Dish41 micrographs - single frame DM4 DM4 26 1 32 BIT FLOAT 4096 37.7 4096 variable
Unaligned serial TEM imaging data of a neuronal cell in culture (dish42) /data/Electron_Microscopy/Dish42 micrographs - single frame DM4 DM4 30 1 32 BIT FLOAT 4096 37.7 4096 variable
Unaligned Serial TEM Imaging data of a neuronal cell in culture (Dish 43) /data/Electron_Microscopy/Dish43 micrographs - single frame DM4 DM4 7 1 32 BIT FLOAT 4096 37.7 4096 variable
FIB-SEM data set of a neuronal cell in culture (Dish 51) /data/Electron_Microscopy/Dish51 micrographs - multiframe TIFF TIFF 1190 1 UNSIGNED BYTE 2337 50.0 4347 50.0
FIB-SEM data of a neuronal cell in culture (Dish 52) /data/Electron_Microscopy/Dish52 micrographs - multiframe TIFF TIFF 1436 1 UNSIGNED BYTE 2000 50.0 3430 50.0
FIB-SEM data of a neuronal cell in culture (Dish 131) /data/Electron_Microscopy/Dish131/Processed micrographs - multiframe TIFF TIFF 1800 1 UNSIGNED BYTE 8152 50.0 1949 50.0
FIB-SEM data of a neuronal cell in culture (Dish 141) /data/Electron_Microscopy/Dish141 micrographs - multiframe TIFF TIFF 1390 1 UNSIGNED BYTE 8393 50.0 3439 50.0