REL 2022-04-28 2023-03-01 2023-03-01 CryoEM structure of Go-coupled 5-HT5AR in complex with Methylergometrine 0000-0003-1822-2384 Jonathan Firoze Fay UNC at Chapel Hill Thurston-Bowles Building Room 6107 Chapel Hill NC United States 27599 0000-0002-0561-6520 Bryan L Roth UNC Department of Pharmacology 4072 Genetic Medicine Building Chapel Hill NC United States 27514 Fay JF Roth BL Zhang S 924.6 10.6019/EMPIAR-11039 EMDB molecule EMD-26599 Zhang S Chen H Zhang C Yang Y Popov P Liu J Krumm BE Cao C Kim K Xiong Y Katritch V Shoichet BK Jin J Fay JF Roth BL Inactive and active state structures template selective tools for the human 5-HT<sub>5A</sub> receptor Nature structural & molecular biology Nat Struct Mol Biol 7 29 677 687 2022 English 10.1038/s41594-022-00796-6 35835867
The micrographs are dose weighted motion corrected 60 frame movies collected on a 200 keV ThermoFisher Scientific G3 Talos Arctica equipped with a Gatan K3 direct-electron detector (total exposure dose ~47.4 e/A^2, 0.91 raw pixel size)
 Aligned multi-frame micrographs /data micrographs - single frame MRC MRC 10530 1 32 BIT FLOAT 5760 0.91 4092 0.91
The micrographs are dose weighted motion corrected with a total electron exposure of 47.4 e/A2
data/*.mrc