<entry xmlns="http://pdbe.org/empiar" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="https://ftp.ebi.ac.uk/pub/databases/emtest/empiar/schema/empiar.xsd" accessionCode="EMPIAR-11007" public="true">
    <admin>
        <currentStatus>REL</currentStatus>
        <keyDates>
            <depositionDate>2022-02-16</depositionDate>
            <releaseDate>2022-05-24</releaseDate>
            <updateDate>2022-05-24</updateDate>
        </keyDates>
        <title>The complex of phosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) with ATP/Mg and Tezacaftor (VX-661)</title>
        <correspondingAuthor>
            <authorORCID>0000-0003-2075-4283</authorORCID>
            <firstName>Jue</firstName>
            <lastName>Chen</lastName>
            <organization type="academic">Laboratory of Membrane Biology and Biophysics, The Rockefeller University</organization>
            <street>1230 York Avenue, Box 233</street>
            <townOrCity>New York</townOrCity>
            <stateOrProvince>NY</stateOrProvince>
            <country>United States</country>
            <postOrZipCode>10065</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator>
            <authorORCID>0000-0003-2075-4283</authorORCID>
            <firstName>Jue</firstName>
            <lastName>Chen</lastName>
            <organization type="academic">Laboratory of Membrane Biology and Biophysics, The Rockefeller University</organization>
            <street>1230 York Avenue, Box 233</street>
            <townOrCity>New York</townOrCity>
            <stateOrProvince>NY</stateOrProvince>
            <country>United States</country>
            <postOrZipCode>10065</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author authorORCID="0000-0001-7439-0222">Fiedorczuk K</author>
            <author authorORCID="0000-0003-2075-4283">Chen J</author>
        </authorsList>
        <datasetSize units="TB">1.8</datasetSize>
        <entryDOI>10.6019/EMPIAR-11007</entryDOI>
        <experimentType>EMDB</experimentType>
    </admin>
    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-25445</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="false">
                    <author authorORCID="0000-0001-7439-0222" order="1">Fiedorczuk K</author>
                    <author authorORCID="0000-0003-2075-4283" order="2">Chen J</author>
                    <title>Mechanism of CFTR correction by type I folding correctors</title>
                    <journal>Cell</journal>
                    <journalAbbreviation>Cell</journalAbbreviation>
                    <country></country>
                    <issue>1</issue>
                    <volume>185</volume>
                    <firstPage>158</firstPage>
                    <lastPage>168</lastPage>
                    <year>2021</year>
                    <language>English</language>
                    <externalReferences type="doi">10.1016/j.cell.2021.12.009</externalReferences>
                    <externalReferences type="pubmed">34995514</externalReferences>
                    <details>The dataset contains super-resolution, raw, uncorrected movies and gain references that have been flipped and rotated by 90 degrees for use. The super-resolution pixel size is 0.515 Angstrom before binning (1.03 Angstrom after binning)</details>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>Unaligned multi-frame micrographs of phosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) with ATP/Mg and Tezacaftor (VX-661)</name>
        <directory>/data</directory>
        <category>micrographs - multiframe</category>
        <headerFormat>TIFF</headerFormat>
        <dataFormat>TIFF</dataFormat>
        <numImagesOrTiltSeries>4257</numImagesOrTiltSeries>
        <framesPerImage>50</framesPerImage>
        <frameRange>
            <frameRangeMin>1</frameRangeMin>
            <frameRangeMax>50</frameRangeMax>
        </frameRange>
        <voxelType>UNSIGNED BYTE</voxelType>
        <dimensions>
            <imageWidth>7420</imageWidth>
            <pixelWidth>0.515</pixelWidth>
            <imageHeight>7676</imageHeight>
            <pixelHeight>0.515</pixelHeight>
        </dimensions>
        <details>The dataset contains super-resolution, raw, uncorrected movies and gain references that have been flipped and rotated by 90 degrees for use. The super-resolution pixel size is 0.515 Angstrom before binning (1.03 Angstrom after binning)</details>
        <segmentationList/>
        <micrographsFilePattern></micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
</entry>
