REL
2022-01-08
2023-01-03
2023-01-03
C-terminal half of Leucine Rich Repeat Kinase 1 (LRRK1)
0000-0003-1033-9270
Mariusz
Matyszewski
CMM, UCSD
9500 Gilman Dr, MC 0694
La Jolla
California
United States
92093
0000-0002-7732-7023
Andres
Leschziner
CMM, UCSD
9500 Gilman Dr, MC 0694
La Jolla
California
United States
92093
Matyszewski M
Leschziner AE
1.2
10.6019/EMPIAR-10921
EMDB
molecule
EMD-25672
Snead DM
Matyszewski M
Dickey AM
Lin YX
Leschziner AE
Reck-Peterson SL
Structural basis for Parkinson's disease-linked LRRK2's binding to microtubules
Nature structural & molecular biology
Nat Struct Mol Biol
12
29
1196
1207
2022
English
10.1038/s41594-022-00863-y
36510024
Publication includes structures of the C-terminal half of LRRK2 (I2020T) bound to microtubules as filaments, as well a structure of the C-terminal half of LRRK1.
Unaligned multi-frame micrographs of the C-terminus of Leucine Rich Repeat Kinase 1 (LRRK1)
/data
micrographs - multiframe
TIFF
TIFF
3629
50
45
55
UNSIGNED 16 BIT INTEGER
3710
1.16
3838
1.16
Contains 4 datasets: 19dec11a, 19dec21c, 20sep11a, 21jan18d.
All had the total dose set to 55 e/A-2.
20sep11a was collected with a 20-degree tilt.
Each dataset has different number of frames due to changes in beam strength.
19dec11a: 50 frames
19dec21c: 45 frames
20sep11a: 55 frames
21jan18d: 55 frames