<entry xmlns="http://pdbe.org/empiar" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="https://ftp.ebi.ac.uk/pub/databases/emtest/empiar/schema/empiar.xsd" accessionCode="EMPIAR-10899" public="true">
    <admin>
        <currentStatus>REL</currentStatus>
        <keyDates>
            <depositionDate>2021-12-10</depositionDate>
            <releaseDate>2022-01-28</releaseDate>
            <updateDate>2022-01-28</updateDate>
        </keyDates>
        <title>CryoEM of Mycobacterium tuberculosis WT RNAP holoenzyme/RbpA bound to an inhibitor corallopyronin and de novo melted AP3 promoter DNA</title>
        <correspondingAuthor>
            <authorORCID>0000-0002-1332-128X</authorORCID>
            <firstName>Elizabeth</firstName>
            <middleName>A</middleName>
            <lastName>Campbell</lastName>
            <organization type="academic">The Rockefeller University</organization>
            <street>1230 York Avenue</street>
            <townOrCity>New York</townOrCity>
            <stateOrProvince>NY</stateOrProvince>
            <country>United States</country>
            <postOrZipCode>10065</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator>
            <authorORCID>0000-0002-1332-128X</authorORCID>
            <firstName>Elizabeth</firstName>
            <middleName>A</middleName>
            <lastName>Campbell</lastName>
            <organization type="academic">The Rockefeller University</organization>
            <street>1230 York Avenue</street>
            <townOrCity>New York</townOrCity>
            <stateOrProvince>NY</stateOrProvince>
            <country>United States</country>
            <postOrZipCode>10065</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author authorORCID="0000-0003-4276-7659">Boyaci H</author>
            <author authorORCID="0000-0002-2311-003X">Chen J</author>
            <author>Jansen R</author>
            <author authorORCID="0000-0002-8241-3153">Darst SA</author>
            <author authorORCID="0000-0002-1332-128X">Campbell EA</author>
        </authorsList>
        <datasetSize units="TB">1.8</datasetSize>
        <entryDOI>10.6019/EMPIAR-10899</entryDOI>
        <experimentType>EMDB</experimentType>
    </admin>
    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-9041</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="false">
                    <author authorORCID="0000-0003-4276-7659" order="1">Boyaci H</author>
                    <author authorORCID="0000-0002-2311-003X" order="2">Chen J</author>
                    <author order="3">Jansen R</author>
                    <author authorORCID="0000-0002-8241-3153" order="4">Darst SA</author>
                    <author authorORCID="0000-0002-1332-128X" order="5">Campbell EA</author>
                    <title>Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding</title>
                    <journal>Nature</journal>
                    <journalAbbreviation>Nature</journalAbbreviation>
                    <country>United States</country>
                    <issue>7739</issue>
                    <volume>565</volume>
                    <firstPage>382</firstPage>
                    <lastPage>385</lastPage>
                    <year>2019</year>
                    <language>English</language>
                    <externalReferences type="doi">10.1038/s41586-018-0840-5</externalReferences>
                    <externalReferences type="pubmed">30626968</externalReferences>
                    <details>The micrographs are the average of 50 raw movie frames, accumulating 71 electrons per squared Angstroms in a 15 seconds exposure time.</details>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>Unaligned multi frame micrographs of M. tuberculosis RNAP/RbpA holoenzyme with CarD and Cor and AP3 promoter DNA</name>
        <directory>/data/20180418</directory>
        <category>micrographs - multiframe</category>
        <headerFormat>TIFF</headerFormat>
        <dataFormat>TIFF</dataFormat>
        <numImagesOrTiltSeries>1777</numImagesOrTiltSeries>
        <framesPerImage>50</framesPerImage>
        <frameRange>
            <frameRangeMin>1</frameRangeMin>
            <frameRangeMax>50</frameRangeMax>
        </frameRange>
        <voxelType>UNSIGNED BYTE</voxelType>
        <dimensions>
            <imageWidth>7420</imageWidth>
            <pixelWidth>0.6625</pixelWidth>
            <imageHeight>7676</imageHeight>
            <pixelHeight>0.6625</pixelHeight>
        </dimensions>
        <details></details>
        <segmentationList/>
        <micrographsFilePattern>data/20180418/MtbHoloRbpa_CarD_Cor_AP3_*.tif</micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
    <imageSet>
        <name>Unaligned multi frame micrographs of M. tuberculosis RNAP/RbpA holoenzyme with CarD and Cor and AP3 promoter DNA</name>
        <directory>/data/20180720</directory>
        <category>micrographs - multiframe</category>
        <headerFormat>TIFF</headerFormat>
        <dataFormat>TIFF</dataFormat>
        <numImagesOrTiltSeries>2067</numImagesOrTiltSeries>
        <framesPerImage>50</framesPerImage>
        <frameRange>
            <frameRangeMin>1</frameRangeMin>
            <frameRangeMax>50</frameRangeMax>
        </frameRange>
        <voxelType>UNSIGNED BYTE</voxelType>
        <dimensions>
            <imageWidth>7420</imageWidth>
            <pixelWidth>0.6625</pixelWidth>
            <imageHeight>7676</imageHeight>
            <pixelHeight>0.6625</pixelHeight>
        </dimensions>
        <details></details>
        <segmentationList/>
        <micrographsFilePattern>data/20180720/MtbHolo_RbpA_CarD_Cor_AP3_*.tif</micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
</entry>
