REL
2021-10-01
2021-12-23
2022-01-24
cryoEM structure of Gq-coupled MRGPRX2 with peptide agonist Cortistatin-14
0000-0003-1822-2384
Jonathan
Firoze
Fay
UNC at Chapel Hill
Thurston-Bowles Building Room 6107
Chapel Hill
NC
United States
27599
0000-0002-0561-6520
Bryan
L
Roth
UNC Department of Pharmacology
4072 Genetic Medicine Building
Chapel Hill
NC
United States
27514
Cao C
Fay J
Roth B
3.6
10.6019/EMPIAR-10853
EMDB
EMD-24896
Cao C
Kang HJ
Singh I
Chen H
Zhang C
Ye W
Hayes BW
Liu J
Gumpper RH
Bender BJ
Slocum ST
Krumm BE
Lansu K
McCorvy JD
Kroeze WK
English JG
DiBerto JF
Olsen RHJ
Huang XP
Zhang S
Liu Y
Kim K
Karpiak J
Jan LY
Abraham SN
Jin J
Shoichet BK
Fay JF
Roth BL
Structure, function and pharmacology of human itch GPCRs
Nature
Nature
United States
7887
600
170
175
2021
English
10.1038/s41586-021-04126-6
34789874
The micrographs are raw tiff 60 frame movies collected on a 200 keV ThermoFisher Scientific G3 Talos Arctica equipped with a Gatan K3 direct-electron detector (total exposure dose 50.74 & 47.87 e/A^2, 0.91 raw pixel size)
Unaligned multi-frame micrographs
/data
micrographs - multiframe
TIFF
TIFF
12299
60
UNSIGNED BYTE
5760
variable
4092
variable