REL
2021-10-23
2022-03-08
2022-03-08
Structure of negative allosteric modulator-bound inactive human calcium-sensing receptor
0000-0002-9330-0963
Qing
Rong
Fan
Department of Molecular Pharmacology and Therapeutics, Columbia University
630 West 168th Street
New York
New York
United States
10032-3725
0000-0002-9330-0963
Qing
Rong
Fan
Department of Molecular Pharmacology and Therapeutics, Columbia University
630 West 168th Street
New York
New York
United States
10032-3725
Park J
Zuo H
Frangaj A
Fu Z
Yen LY
Zhang Z
Mosyak L
Slavkovich VN
Liu J
Ray KM
Cao B
Vallese F
Geng Y
Chen S
Grassucci R
Dandey VP
Tan YZ
Eng E
Lee Y
Kloss B
Liu Z
Hendrickson WA
Potter CS
Carragher B
Graziano J
Conigrave AD
Frank J
Clarke OB
Fan QR
4.0
10.6019/EMPIAR-10835
EMDB
EMD-25145
Park J
Zuo H
Frangaj A
Fu Z
Yen LY
Zhang Z
Mosyak L
Slavkovich VN
Liu J
Ray KM
Cao B
Vallese F
Geng Y
Chen S
Grassucci R
Dandey VP
Tan YZ
Eng E
Lee Y
Kloss B
Liu Z
Hendrickson WA
Potter CS
Carragher B
Graziano J
Conigrave AD
Frank J
Clarke OB
Fan QR
Symmetric activation and modulation of the human calcium-sensing receptor
Proceedings of the National Academy of Sciences of the United States of America
Proc Natl Acad Sci U S A
United States
51
118
2021
English
10.1073/pnas.2115849118
34916296
Unaligned multi-frame micrographs. The inactive-state dataset consists of micrographs with 50 raw movie frames (accumulating 58.63 electrons per squared Angstrom in a 2.5 second exposure).
Unaligned multi-frame micrographs of calcium-sensing receptor in NAM-bound inactive state
/data
micrographs - multiframe
TIFF
TIFF
15464
50
1
50
UNSIGNED BYTE
5760
0.83
4092
0.83
Unaligned multi-frame micrographs (50 frames per movie accumulating 58.63 electrons per squared Angstrom in a 2.5 second exposure).
data/20sep21a*.tif