<entry xmlns="http://pdbe.org/empiar" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="https://ftp.ebi.ac.uk/pub/databases/emtest/empiar/schema/empiar.xsd" accessionCode="EMPIAR-10824" public="true">
    <admin>
        <currentStatus>REL</currentStatus>
        <keyDates>
            <depositionDate>2021-09-15</depositionDate>
            <releaseDate>2021-10-26</releaseDate>
            <updateDate>2021-10-26</updateDate>
        </keyDates>
        <title>Cryo electron micrographs of Pol delta-DNA-PCNA giving rise to various PCNA tilt angles</title>
        <correspondingAuthor>
            <authorORCID>0000-0001-9064-4085</authorORCID>
            <firstName>Claudia</firstName>
            <lastName>Lancey</lastName>
            <organization type="academic">Department of Molecular &amp;amp; Cell Biology, University of Leicester</organization>
            <street>University Road</street>
            <townOrCity>Leicester</townOrCity>
            <stateOrProvince>Leicestershire</stateOrProvince>
            <country>United Kingdom</country>
            <postOrZipCode>LE1 7RH</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator>
            <authorORCID>0000-0003-2139-2958</authorORCID>
            <firstName>Alfredo</firstName>
            <lastName>De Biasio</lastName>
            <organization type="academic">King Abdullah University of Science and Technology</organization>
            <street>King Abdullah University of Science and Technology</street>
            <townOrCity>Thuwal</townOrCity>
            <stateOrProvince>Thuwal</stateOrProvince>
            <country>Saudi Arabia</country>
            <postOrZipCode>23955-6900</postOrZipCode>
        </principalInvestigator>
        <principalInvestigator>
            <authorORCID>0000-0001-5192-1852</authorORCID>
            <firstName>Samir</firstName>
            <lastName>Hamdan</lastName>
            <organization type="academic">King Abdullah University of Science and Technology</organization>
            <street>King Abdullah University of Science and Technology</street>
            <townOrCity>Thuwal</townOrCity>
            <stateOrProvince>Thuwal</stateOrProvince>
            <country>Saudi Arabia</country>
            <postOrZipCode>23955-6900</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author authorORCID="0000-0001-9064-4085">Lancey C</author>
            <author authorORCID="0000-0001-9834-2372">Tehseen M</author>
            <author authorORCID="0000-0001-6722-9262">Raducanu VS</author>
            <author authorORCID="0000-0003-3898-3842">Rashid F</author>
            <author authorORCID="0000-0003-0721-4813">Merino N</author>
            <author authorORCID="0000-0002-6233-3375">Ragan TJ</author>
            <author authorORCID="0000-0003-3354-6483">Savva CG</author>
            <author authorORCID="0000-0002-7785-4384">Zaher MS</author>
            <author authorORCID="0000-0002-3559-7594">Shirbini A</author>
            <author authorORCID="0000-0003-2545-4319">Blanco FJ</author>
            <author authorORCID="0000-0001-5192-1852">Hamdan SM</author>
            <author authorORCID="0000-0003-2139-2958">De Biasio A</author>
        </authorsList>
        <datasetSize units="TB">3.6</datasetSize>
        <entryDOI>10.6019/EMPIAR-10824</entryDOI>
        <experimentType>EMDB</experimentType>
    </admin>
    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-10080</emdbEntry>
            <emdbEntry>EMD-10081</emdbEntry>
            <emdbEntry>EMD-10082</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="false">
                    <author authorORCID="0000-0001-9064-4085" order="1">Lancey C</author>
                    <author authorORCID="0000-0001-9834-2372" order="2">Tehseen M</author>
                    <author authorORCID="0000-0001-6722-9262" order="3">Raducanu VS</author>
                    <author authorORCID="0000-0003-3898-3842" order="4">Rashid F</author>
                    <author authorORCID="0000-0003-0721-4813" order="5">Merino N</author>
                    <author authorORCID="0000-0002-6233-3375" order="6">Ragan TJ</author>
                    <author authorORCID="0000-0003-3354-6483" order="7">Savva CG</author>
                    <author authorORCID="0000-0002-7785-4384" order="8">Zaher MS</author>
                    <author authorORCID="0000-0002-3559-7594" order="9">Shirbini A</author>
                    <author authorORCID="0000-0003-2545-4319" order="10">Blanco FJ</author>
                    <author authorORCID="0000-0001-5192-1852" order="11">Hamdan SM</author>
                    <author authorORCID="0000-0003-2139-2958" order="12">De Biasio A</author>
                    <title>Structure of the processive human Pol δ holoenzyme</title>
                    <journal>Nature communications</journal>
                    <journalAbbreviation>Nat Commun</journalAbbreviation>
                    <country></country>
                    <issue>1</issue>
                    <volume>11</volume>
                    <year>2020</year>
                    <language>English</language>
                    <externalReferences type="doi">10.1038/s41467-020-14898-6</externalReferences>
                    <externalReferences type="pubmed">32111820</externalReferences>
                    <details>This entry contains 3 datasets taken from 2 identically prepared grids. The data were combined for processing.</details>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>Cryo-electron micrographs of Pol delta holoenzyme giving rise to different tilted conformers, collection 2</name>
        <directory>/data/PolD-Term2_20190329_104527</directory>
        <category>micrographs - multiframe</category>
        <headerFormat>MRC</headerFormat>
        <dataFormat>MRC</dataFormat>
        <numImagesOrTiltSeries>1406</numImagesOrTiltSeries>
        <framesPerImage>75</framesPerImage>
        <voxelType>SIGNED 16 BIT INTEGER</voxelType>
        <dimensions>
            <imageWidth>4096</imageWidth>
            <pixelWidth>1.081</pixelWidth>
            <imageHeight>4096</imageHeight>
            <pixelHeight>1.081</pixelHeight>
        </dimensions>
        <details>Images taken on a FEI Titan Krios G3 at 300kV with a Falcon 3 detector. Defocus -0.6 micrometers. Volta phase plate was used. Total dose = 36 e-/Å^2. Dataset includes 3 corrupted files, as file names suggest - these became corrupted after the deposited EMDB maps were obtained.</details>
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        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
    <imageSet>
        <name>Cryo-electron micrographs of Pol delta holoenzyme giving rise to different tilted conformers, collection 1</name>
        <directory>/data/PolD_term_20190325_134912</directory>
        <category>micrographs - multiframe</category>
        <headerFormat>MRC</headerFormat>
        <dataFormat>MRC</dataFormat>
        <numImagesOrTiltSeries>452</numImagesOrTiltSeries>
        <framesPerImage>75</framesPerImage>
        <voxelType>SIGNED 16 BIT INTEGER</voxelType>
        <dimensions>
            <imageWidth>4096</imageWidth>
            <pixelWidth>1.081</pixelWidth>
            <imageHeight>4096</imageHeight>
            <pixelHeight>1.081</pixelHeight>
        </dimensions>
        <details>Images taken on a FEI Titan Krios G3 at 300kV with a Falcon 3 detector. Defocus -0.4 micrometers. Volta phase plate was used. Total dose = 36 e-/Å^2. Dataset includes 2 corrupted files, as file names suggest - these became corrupted after the deposited EMDB maps were obtained.</details>
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    <imageSet>
        <name>Cryo-electron micrographs of Pol delta holoenzyme giving rise to different tilted conformers, collection 3</name>
        <directory>/data/supervisor_20190420_104259</directory>
        <category>micrographs - multiframe</category>
        <headerFormat>MRC</headerFormat>
        <dataFormat>MRC</dataFormat>
        <numImagesOrTiltSeries>1717</numImagesOrTiltSeries>
        <framesPerImage>75</framesPerImage>
        <voxelType>SIGNED 16 BIT INTEGER</voxelType>
        <dimensions>
            <imageWidth>4096</imageWidth>
            <pixelWidth>1.081</pixelWidth>
            <imageHeight>4096</imageHeight>
            <pixelHeight>1.081</pixelHeight>
        </dimensions>
        <details>Images taken on a FEI Titan Krios G3 at 300kV with a Falcon 3 detector. Defocus -0.6 micrometers. Volta phase plate was used. Total dose = 36 e-/Å^2.</details>
        <segmentationList/>
        <micrographsFilePattern>data/supervisor_20190420_104259/Images-Disc1/GridSquare_*/Data/*_Fractions.mrc.bz2</micrographsFilePattern>
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