Human DPP9-CARD8 complex-VbP

REL 2020-12-13 2021-05-25 2022-02-15 Human DPP9-CARD8 complex-VbP 0000-0002-7281-8579 Hao Wu Harvard Medical School Boston MA United States 02115 0000-0002-7281-8579 Hao Wu Harvard Medical School Boston MA United States 02115 Sharif H Hollingsworth LR Griswold AR Hsiao JC Wang Q Bachovchin DA Wu H 2.1 10.6019/EMPIAR-10596 EMDB EMD-22402 Sharif H Hollingsworth LR Griswold AR Hsiao JC Wang Q Bachovchin DA Wu H Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment Immunity Immunity 7 54 1392 1404.e10 2021 English 10.1016/j.immuni.2021.04.024 34019797 Unaligned multi frame micographs of CARD8-DPP9-VbP-noTILT /data/CARD_DPP9_VbP_Raw_Movies_noTILT micrographs - multiframe TIFF TIFF 1811 50 UNSIGNED BYTE variable 0.82 variable 0.82

For CARD8-DPP9-VbP 1,811 movies were collected at varying defocus levels ranging between −1.1 to −3.4 μm. One shot was recorded for each of the four holes per stage movement through image shift. All movies were exposed with a total dose of 67.06 e-/Å2 for 1.5 s fractionated over 50 frames. "references" folder contains the references.

Unaligned multi frame micographs of CARD8-DPP9-VbP-TILT /data/CARD_DPP9_VbP_Raw_Movies_TILT micrographs - multiframe TIFF TIFF 6642 50 UNSIGNED BYTE variable 0.82 variable 0.82

For CARD8-DPP9-VbP tilt data, 6,642 movies at a stage tilt of 37° were collected at varying defocus levels ranging between −1.1 to −3.4 μm. One shot was recorded for each of the four holes per stage movement through image shift. All movies were exposed with a total dose of 67.06 e-/Å2 for 1.5 s fractionated over 50 frames. "references" folder contains the references.