REL 2020-05-04 2021-11-09 2021-11-09 0000-0002-9330-0963 Qing Rong Fan Department of Pharmacology, Department of Pathology and Cell Biology, Columbia University 630 West 168th Street New York New York United States 10032 0000-0002-9330-0963 Qing R Fan Department of Pharmacology, Department of Pathology and Cell Biology, Columbia University 630 West 168th Street New York New York United States 10032 0000-0001-5449-6943 Joachim Frank Department of Biochemistry and Molecular Biophysics, Department of Biological Sciences, Columbia University 630 West 168th Street New York New York United States 10032 0000-0003-1876-196X Oliver B Clarke Department of Physiology and Cellular Biophysics, Department of Anesthesiology, Columbia University 630 West 168th Street New York New York United States 10032 Park J Fu Z Frangaj A Liu J Mosyak L Shen T Slavkovich VN Ray KM Taura J Cao B Geng Y Zuo H Kou Y Grassucci R Chen S Liu Z Lin X Williams JP Rice WJ Eng ET Huang RK Soni RK Kloss B Yu Z Javitch JA Hendrickson WA Slesinger PA Quick M Graziano J Yu H Fiehn O Clarke OB Frank J Fan QR 854.1 10.6019/EMPIAR-10410 EMDB EMD-21685 Park J Fu Z Frangaj A Liu J Mosyak L Shen T Slavkovich VN Ray KM Taura J Cao B Geng Y Zuo H Kou Y Grassucci R Chen S Liu Z Lin X Williams JP Rice WJ Eng ET Huang RK Soni RK Kloss B Yu Z Javitch JA Hendrickson WA Slesinger PA Quick M Graziano J Yu H Fiehn O Clarke OB Frank J Fan QR Nature Nature 7820 584 304 309 2020 English 10.1038/s41586-020-2452-0 32581365

Each raw-multiframe micrograph possesses 60 frames over a 12 second duration, exposed to a total of 85 electrons per squared Angstrom.

Unaligned multi-frame micrographs of GABA(B) receptor in the inactive state /data/raw_multiframe_micrographs micrographs - multiframe MRC MRC 3435 60 UNSIGNED 16 BIT INTEGER 3710 1.06 3838 1.06

Micrographs are 3-D volumes of 60 frames without realignment, totaling 85 electrons per squared Angstrom during a 12 second exposure. Gain and dark references are included with the dataset as well.