REL
2019-10-01
2021-11-08
2021-11-08
Hedgehog receptor Patched (PTCH1) in complex with a conformation selective nanobody TI23
0000-0003-2145-4151
Yunxiao
Zhang
Stanford University
265 Campus Drive
Stanford
CA
United States
94305
0000-0003-1098-9046
Philip
Arden
Beachy
Stanford University
265 Campus Drive
Stanford
CA
United States
94305
Zhang Y
Lu WJ
Bulkley DP
Liang J
Ralko A
Han S
Roberts KJ
Li A
Cho W
Cheng Y
Manglik A
Beachy PA
75.2
10.6019/EMPIAR-10328
EMDB
EMD-22689
Zhang Y
Lu WJ
Bulkley DP
Liang J
Ralko A
Han S
Roberts KJ
Li A
Cho W
Cheng Y
Manglik A
Beachy PA
Hedgehog pathway activation through nanobody-mediated conformational blockade of the Patched sterol conduit
Proceedings of the National Academy of Sciences of the United States of America
Proc Natl Acad Sci U S A
46
117
28838
28846
2020
English
10.1073/pnas.2011560117
33139559
Particle stack of Hedgehog receptor PTCH1 in complex with nanobody TI23 for final reconstruction
/data
picked particles - multiframe - processed
MRCS
MRCS
307652
1
32 BIT FLOAT
256
1.059
256
1.059
This is the particle stack for the final reconstruction of PTCH1-TI23 complex. The data sign is +1, white particle on dark background. The accompanying star file is exported from the last round of refinement in cryoSPARC2, with all the CTF parameters recorded.