<entry xmlns="http://pdbe.org/empiar" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="https://ftp.ebi.ac.uk/pub/databases/emtest/empiar/schema/empiar.xsd" accessionCode="EMPIAR-10281" schemaVersion="0.65" public="true">
    <admin>
        <currentStatus>REL</currentStatus>
        <keyDates>
            <depositionDate>2019-06-06</depositionDate>
            <releaseDate>2019-06-21</releaseDate>
            <updateDate>2019-07-08</updateDate>
        </keyDates>
        <title>Cryo electron micrographs of human cystic fibrosis transmembrane conductance regulator (CFTR) in complex with GLPG</title>
        <correspondingAuthor private="true">
            <firstName>Jue</firstName>
            <lastName>Chen</lastName>
            <organization type="academic">The Rockefeller University</organization>
            <street>1230 York Avenue</street>
            <townOrCity>New York</townOrCity>
            <stateOrProvince>New York</stateOrProvince>
            <country>United States</country>
            <postOrZipCode>10065</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator private="true">
            <firstName>Jue</firstName>
            <lastName>Chen</lastName>
            <organization type="academic">The Rockefeller University</organization>
            <street>1230 York Avenue</street>
            <townOrCity>New York</townOrCity>
            <stateOrProvince>New York</stateOrProvince>
            <country>United States</country>
            <postOrZipCode>10065</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author authorORCID="0000-0002-4932-4343">Zhang ZZ</author>
            <author>Liu FL</author>
            <author>Chen JC</author>
        </authorsList>
        <datasetSize units="TB">1.4</datasetSize>
        <entryDOI>10.6019/EMPIAR-10281</entryDOI>
        <experimentType>EMDB</experimentType>
    </admin>
    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-0606</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="false">
                    <author order="1">Liu FL</author>
                    <author authorORCID="0000-0002-4932-4343" order="2">Zhang ZZ</author>
                    <author order="3">Levit AL</author>
                    <author order="4">Levring JL</author>
                    <author order="5">Touhara KT</author>
                    <author order="6">Shoichet BS</author>
                    <author order="7">Chen JC</author>
                    <title>Structural identification of a hotspot on CFTR for potentiation</title>
                    <journal>Science</journal>
                    <journalAbbreviation>Science</journalAbbreviation>
                    <country>United States</country>
                    <year>2019</year>
                    <language>English</language>
                    <externalReferences type="doi">10.1126/science.aaw7611</externalReferences>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>Unaligned multi-frame micrographs of human CFTR in complex with GLPG1837</name>
        <directory>/data/tiffs</directory>
        <category>micrographs - multiframe</category>
        <headerFormat>TIFF</headerFormat>
        <dataFormat>TIFF</dataFormat>
        <numImagesOrTiltSeries>3335</numImagesOrTiltSeries>
        <framesPerImage>50</framesPerImage>
        <frameRange>
            <frameRangeMin>1</frameRangeMin>
            <frameRangeMax>50</frameRangeMax>
        </frameRange>
        <voxelType>UNSIGNED BYTE</voxelType>
        <dimensions>
            <imageWidth>7420</imageWidth>
            <pixelWidth>variable</pixelWidth>
            <imageHeight>7676</imageHeight>
            <pixelHeight>variable</pixelHeight>
        </dimensions>
        <details>The gain reference file is named as Gainreference.mrc and is put in the same folder as the movies.</details>
        <segmentationList/>
        <micrographsFilePattern>data/tiffs/1837_*.tif</micrographsFilePattern>
        <pickedParticlesFilePattern>data/particles.star</pickedParticlesFilePattern>
        <pickedParticlesDirectory>data/tiffs</pickedParticlesDirectory>
    </imageSet>
</entry>
