REL
2019-01-28
2019-04-25
2019-04-25
CryoEM micrographs of ProTx2-bound Nav1.7 VSD2-NavAb chimeric channel
0000-0002-3343-9621
Alexis
Lawrence
Rohou
Department of Structural Biology, Genentech
1 DNA Way
South San Francisco
CA
United States
94080
0000-0002-3343-9621
Alexis
Lawrence
Rohou
Department of Structural Biology, Genentech
1 DNA Way
South San Francisco
CA
United States
94080
Xu H
Li T
Rohou A
Arthur CP
Tzakoniati F
Wong E
Estevez A
Kugel C
Franke Y
Chen J
Ciferri C
Hackos DH
Koth CM
Payandeh J
2.8
10.6019/EMPIAR-10261
EMDB
EMD-0341
Rohou A
Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin
Cell
Cell
176
2019
English
10.1016/j.cell.2018.12.018
30661758
Raw, non-gain-corrected frames, in TIF-LZW format, as saved by SerialEM. Stacks of 40 frames, recorded over 10 seconds. Pixel size 0.849 Å. Gain reference image is saved as a DM4 file.
There are two datasets, collected from the same grid, but approx 4 weeks apart.
Dataset 1 (dated 180517): total exposure = 41.6 e/Å^2; exp/frame = 1.041 e/Å^2
Dataset 2 (dated 180614): total exposure = 34.7 e/Å^2; exp/frame = 0.867 e/Å^2
SerialEM files (navigator, low-mag and medium-mag montages) are also included.
First dataset - raw, compressed, non-gain-corrected, integer frames
/data/180517_Nav_708AA_ProTxII_7A9/Data
micrographs - multiframe
TIFF
TIFF
12872
40
UNSIGNED BYTE
3838
0.849
3710
0.849
Raw, non-gain-corrected frames, in TIF-LZW format, as saved by SerialEM. Stacks of 40 frames, recorded over 10 seconds. Pixel size 0.849 Å. Gain reference image is saved as a DM4 file.
There are two datasets, collected from the same grid, but approx 4 weeks apart.
Dataset 1 (dated 180517): total exposure = 41.6 e/Å^2; exp/frame = 1.041 e/Å^2; 12,872 movies
Dataset 2 (dated 180614): total exposure = 34.7 e/Å^2; exp/frame = 0.867 e/Å^2; 12,212 movies
SerialEM files (navigator, low-mag and medium-mag montages) are also included.
Second dataset - raw, compressed, non-gain-corrected, integer frames
/data/180614_Nav_708AA_ProTxII_7A9/Data
micrographs - multiframe
TIFF
TIFF
12212
40
UNSIGNED BYTE
3838
0.849
3710
0.849
Raw, non-gain-corrected frames, in TIF-LZW format, as saved by SerialEM. Stacks of 40 frames, recorded over 10 seconds. Pixel size 0.849 Å. Gain reference image is saved as a DM4 file.
There are two datasets, collected from the same grid, but approx 4 weeks apart.
Dataset 1 (dated 180517): total exposure = 41.6 e/Å^2; exp/frame = 1.041 e/Å^2; 12,872 movies
Dataset 2 (dated 180614): total exposure = 34.7 e/Å^2; exp/frame = 0.867 e/Å^2; 12,212 movies
SerialEM files (navigator, low-mag and medium-mag montages) are also included.