<entry xmlns="http://pdbe.org/empiar" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="https://ftp.ebi.ac.uk/pub/databases/emtest/empiar/schema/empiar.xsd" accessionCode="EMPIAR-10258" schemaVersion="0.65" public="true">
    <admin>
        <currentStatus>REL</currentStatus>
        <keyDates>
            <depositionDate>2019-02-28</depositionDate>
            <releaseDate>2019-04-12</releaseDate>
            <updateDate>2019-04-12</updateDate>
        </keyDates>
        <title>LRRC8A-DCPIB in MSP1E3D1 nanodiscs</title>
        <correspondingAuthor private="true">
            <authorORCID>0000-0001-6768-3406</authorORCID>
            <firstName>Stephen</firstName>
            <middleName>G</middleName>
            <lastName>Brohawn</lastName>
            <organization type="academic">UC Berkeley</organization>
            <street>Life Sciences Addition</street>
            <townOrCity>Berkeley</townOrCity>
            <stateOrProvince>California</stateOrProvince>
            <country>United States</country>
            <postOrZipCode>94720</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator private="true">
            <authorORCID>0000-0001-8529-9045</authorORCID>
            <firstName>David</firstName>
            <middleName>M</middleName>
            <lastName>Kern</lastName>
            <organization type="academic">UC Berkeley</organization>
            <street>Life Sciences Addition</street>
            <townOrCity>Berkeley</townOrCity>
            <stateOrProvince>California</stateOrProvince>
            <country>United States</country>
            <postOrZipCode>94720</postOrZipCode>
        </principalInvestigator>
        <principalInvestigator private="true">
            <authorORCID>0000-0003-0496-0669</authorORCID>
            <firstName>Richard</firstName>
            <middleName>K</middleName>
            <lastName>Hite</lastName>
            <organization type="academic">Memorial Sloan Kettering Cancer Center</organization>
            <townOrCity>New York</townOrCity>
            <stateOrProvince>New York</stateOrProvince>
            <country>United States</country>
            <postOrZipCode>10065</postOrZipCode>
        </principalInvestigator>
        <principalInvestigator private="true">
            <authorORCID>0000-0002-1685-5922</authorORCID>
            <firstName>SeCheol</firstName>
            <lastName>Oh</lastName>
            <organization type="academic">Memorial Sloan Kettering Cancer Center</organization>
            <townOrCity>New York</townOrCity>
            <stateOrProvince>New York</stateOrProvince>
            <country>United States</country>
            <postOrZipCode>10065</postOrZipCode>
        </principalInvestigator>
        <principalInvestigator private="true">
            <authorORCID>0000-0001-6768-3406</authorORCID>
            <firstName>Stephen</firstName>
            <middleName>G</middleName>
            <lastName>Brohawn</lastName>
            <organization type="academic">UC Berkeley</organization>
            <street>Life Sciences Addition</street>
            <townOrCity>Berkeley</townOrCity>
            <stateOrProvince>California</stateOrProvince>
            <country>United States</country>
            <postOrZipCode>94720</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author authorORCID="0000-0001-8529-9045">Kern DM</author>
            <author authorORCID="0000-0002-1685-5922">Oh S</author>
            <author authorORCID="0000-0003-0496-0669">Hite RK</author>
            <author authorORCID="0000-0001-6768-3406">Brohawn SG</author>
        </authorsList>
        <datasetSize units="GB">973.9</datasetSize>
        <entryDOI>10.6019/EMPIAR-10258</entryDOI>
        <experimentType>EMDB</experimentType>
    </admin>
    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-0562</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="false">
                    <author authorORCID="0000-0001-8529-9045" order="1">Kern DM</author>
                    <author authorORCID="0000-0002-1685-5922" order="2">Oh S</author>
                    <author authorORCID="0000-0003-0496-0669" order="3">Hite RK</author>
                    <author authorORCID="0000-0001-6768-3406" order="4">Brohawn SG</author>
                    <title>Cryo-EM structures of the DCPIB-inhibited volume-regulated anion channel LRRC8A in lipid nanodiscs</title>
                    <journal>eLife</journal>
                    <journalAbbreviation>Elife</journalAbbreviation>
                    <country></country>
                    <volume>8</volume>
                    <year>2019</year>
                    <language>English</language>
                    <externalReferences type="doi">10.7554/elife.42636</externalReferences>
                    <externalReferences type="pubmed">30775971</externalReferences>
                    <details>Movies without realignment as 40 subframes (accumulating 60.8 electron per squared angstrom over 8 seconds of exposure time). From MSKCC. Gain reference should be rotated 90 degrees and flipped upside down.</details>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>LRRC8A-DCPIB in MSP1E3D1 nanodiscs</name>
        <directory>/data/20180504-tif</directory>
        <category>micrographs - multiframe</category>
        <headerFormat>TIFF</headerFormat>
        <dataFormat>TIFF</dataFormat>
        <numImagesOrTiltSeries>2482</numImagesOrTiltSeries>
        <framesPerImage>40</framesPerImage>
        <frameRange>
            <frameRangeMin>1</frameRangeMin>
            <frameRangeMax>40</frameRangeMax>
        </frameRange>
        <voxelType>UNSIGNED BYTE</voxelType>
        <dimensions>
            <imageWidth>7420</imageWidth>
            <pixelWidth>0.544</pixelWidth>
            <imageHeight>7676</imageHeight>
            <pixelHeight>0.544</pixelHeight>
        </dimensions>
        <details>The gain reference and defects file are in same folder as the movies.</details>
        <segmentationList/>
        <micrographsFilePattern></micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
</entry>
