REL
2018-05-31
2018-06-20
2021-08-24
An atomic structure of human gamma-secretase
0000-0002-0462-6540
Sjors
Scheres
MRC Laboratory of Molecular Biology
Francis Crick Avenue
Cambridge
Cambridgeshire
United Kingdom
CB2 0QH
0000-0002-0462-6540
Sjors
Scheres
MRC Laboratory of Molecular Biology
Francis Crick Avenue
Cambridge
Cambridgeshire
United Kingdom
CB2 0QH
Bai XC
Yan C
Yang G
Lu P
Ma D
Sun L
Zhou R
Scheres SHW
Shi Y
11.7
10.6019/EMPIAR-10194
EMDB
EMD-3061
Bai XC
Yan C
Yang G
Lu P
Ma D
Sun L
Zhou R
Scheres SHW
Shi Y
An atomic structure of human γ-secretase
Nature
Nature
7568
525
212
217
2015
English
10.1038/nature14892
26280335
The micrographs are gain-corrected Falcon-II (integrating mode) movies. A RELION STAR file with the particles used to calculate the 3.4A structure reported in the original paper is also included.
Unaligned multi-frame micrographs of human gamma-secretase
/data
micrographs - multiframe
MRCS
MRCS
2925
20
1
20
32 BIT FLOAT
7420
1.4
7420
1.4
Coordinates for the 412,272 particles used for polishing are in shiny_412272_data.star. Coordinates for the 159,549 particles used for the final 3.4A refinement are in shiny_159549_data.star. Both star files are in RELION format and also contain other metadata necessary for refinement in RELION.